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Posterior Ventricular Enlargement to Differentiate Dementia with Lewy Bodies from Alzheimer's Disease

DC Field Value Language
dc.contributor.author손영호-
dc.contributor.author이필휴-
dc.contributor.author함지현-
dc.contributor.author예병석-
dc.contributor.author이윤주-
dc.contributor.author이재정-
dc.date.accessioned2017-10-26T07:36:39Z-
dc.date.available2017-10-26T07:36:39Z-
dc.date.issued2016-
dc.identifier.issn1387-2877-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/152271-
dc.description.abstractBACKGROUND: Enlargement of the lateral ventricle is observed in dementia associated with Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). OBJECTIVE: The degree of anteroposterior ventricular enlargement and its correlation with clinical and neuropsychological features were investigated in DLB patients. METHODS: Forty-eight patients with DLB, 76 with AD, and 45 subjects with normal cognition (NC) underwent structural brain MRI and detailed neuropsychological tests. Ventricular shape was compared among the groups by visual inspection. Posterior ventricle enlargement (PVE) was defined as the ratio of the distance between the temporal and occipital horns of the lateral ventricle to the distance between the temporal horn of the lateral ventricle and occipital pole of the brain. RESULTS: After controlling for age, sex, and education, higher PVE was observed in the DLB group than in the AD group (68.5 ± 7.9% versus 62.8 ± 9.0%, respectively; p?=?0.001) or the NC group (61.9 ± 9.9%, p?=?0.002). However, higher PVE was not associated with poorer neuropsychological performance, nor was it associated with any clinical features in the DLB group after controlling for age, sex, and education. CONCLUSION: PVE occurs more often in DLB than in AD and NC. However, it is unclear how PVE is related to the clinical and neuropsychological features of DLB.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherIOS Press-
dc.relation.isPartOfJOURNAL OF ALZHEIMERS DISEASE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHAlzheimer Disease/diagnosis*-
dc.subject.MESHAlzheimer Disease/diagnostic imaging-
dc.subject.MESHAlzheimer Disease/pathology-
dc.subject.MESHBrain/diagnostic imaging-
dc.subject.MESHBrain/pathology-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHLateral Ventricles/diagnostic imaging-
dc.subject.MESHLateral Ventricles/pathology*-
dc.subject.MESHLewy Body Disease/diagnosis*-
dc.subject.MESHLewy Body Disease/diagnostic imaging-
dc.subject.MESHLewy Body Disease/pathology-
dc.subject.MESHMagnetic Resonance Imaging-
dc.subject.MESHMale-
dc.subject.MESHNeuroimaging-
dc.subject.MESHNeuropsychological Tests-
dc.subject.MESHOccipital Lobe/diagnostic imaging-
dc.subject.MESHOccipital Lobe/pathology-
dc.subject.MESHTemporal Lobe/diagnostic imaging-
dc.subject.MESHTemporal Lobe/pathology-
dc.titlePosterior Ventricular Enlargement to Differentiate Dementia with Lewy Bodies from Alzheimer's Disease-
dc.typeArticle-
dc.publisher.locationNetherlands-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Neurology-
dc.contributor.googleauthorYe, Byoung Seok-
dc.contributor.googleauthorLee, Yoonju-
dc.contributor.googleauthorKwak, Kichang-
dc.contributor.googleauthorPark, Yeong-Hun-
dc.contributor.googleauthorHam, Jee Hyun-
dc.contributor.googleauthorLee, Jae Jung-
dc.contributor.googleauthorShin, Na-Young-
dc.contributor.googleauthorLee, Jong-Min-
dc.contributor.googleauthorSohn, Young H.-
dc.contributor.googleauthorLee, Phil Hyu-
dc.identifier.doi10.3233/JAD-160062-
dc.contributor.localIdA03270-
dc.contributor.localIdA04338-
dc.contributor.localIdA04603-
dc.contributor.localIdA03024-
dc.contributor.localIdA03082-
dc.contributor.localIdA01982-
dc.relation.journalcodeJ01231-
dc.identifier.eissn1875-8908-
dc.identifier.pmid27104902-
dc.identifier.urlhttp://content.iospress.com/articles/journal-of-alzheimers-disease/jad160062-
dc.subject.keywordAlzheimer’s disease-
dc.subject.keyworddementia with Lewy bodies-
dc.subject.keywordventricular enlargement-
dc.contributor.alternativeNameSohn, Young Ho-
dc.contributor.alternativeNameLee, Phil Hyu-
dc.contributor.alternativeNameHam, Jee Hyun-
dc.contributor.alternativeNameYe, Byoung Seok-
dc.contributor.alternativeNameLee, Yoon Ju-
dc.contributor.alternativeNameLee, Jae Jung-
dc.contributor.affiliatedAuthorLee, Phil Hyu-
dc.contributor.affiliatedAuthorHam, Jee Hyun-
dc.contributor.affiliatedAuthorYe, Byoung Seok-
dc.contributor.affiliatedAuthorLee, Yoon Ju-
dc.contributor.affiliatedAuthorLee, Jae Jung-
dc.contributor.affiliatedAuthorSohn, Young Ho-
dc.citation.volume52-
dc.citation.number4-
dc.citation.startPage1237-
dc.citation.endPage1243-
dc.identifier.bibliographicCitationJOURNAL OF ALZHEIMERS DISEASE, Vol.52(4) : 1237-1243, 2016-
dc.date.modified2017-10-24-
dc.identifier.rimsid48007-
dc.type.rimsART-
Appears in Collections:
6. Others (기타) > Dept. of Health Promotion (건강의학과) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers

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