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A Multicenter Retrospective Case Study of Anaphylaxis Triggers by Age in Korean Children

Authors
 So-Yeon Lee  ;  Kangmo Ahn  ;  Jihyun Kim  ;  Gwang Cheon Jang  ;  Taek Ki Min  ;  Hyeon-Jong Yang  ;  Bok Yang Pyun  ;  Ji-Won Kwon  ;  Myung Hyun Sohn  ;  Kyung Won Kim  ;  Kyu-Earn Kim  ;  Jinho Yu  ;  Soo-Jong Hong  ;  Jung Hyun Kwon  ;  Sung-Won Kim  ;  Tae Won Song  ;  Woo Kyung Kim  ;  Hyung Young Kim  ;  You Hoon Jeon  ;  Yong Ju Lee  ;  Hae Ran Lee  ;  Hye-Young Kim  ;  Youngmin Ahn  ;  Hye Yung Yum  ;  Dong In Suh  ;  Hyun Hee Kim  ;  Jin-Tack Kim  ;  Jeong Hee Kim  ;  Yong Mean Park  ;  Sooyoung Lee 
Citation
 Allergy Asthma & Immunology Research, Vol.8(6) : 353-540, 2016 
Journal Title
 Allergy Asthma & Immunology Research 
ISSN
 2092-7355 
Issue Date
2016
Keywords
Anaphylaxis ; children ; epidemiology
Abstract
PURPOSE: Although anaphylaxis is recognized as an important, life-threatening condition, data are limited regarding its triggers in different age groups. We aimed to identify anaphylaxis triggers by age in Korean children. METHODS: We performed a retrospective review of medical records for children diagnosed with anaphylaxis between 2009 and 2013 in 23 secondary or tertiary hospitals in South Korea. RESULTS: A total of 991 cases (mean age=5.89±5.24) were reported, with 63.9% involving patients younger than 6 years of age and 66% involving male children. Food was the most common anaphylaxis trigger (74.7%), followed by drugs and radiocontrast media (10.7%), idiopathic factors (9.2%), and exercise (3.6%). The most common food allergen was milk (28.4%), followed by egg white (13.6%), walnut (8.0%), wheat (7.2%), buckwheat (6.5%), and peanut (6.2%). Milk and seafood were the most common anaphylaxis triggers in young and older children, respectively. Drug-triggered anaphylaxis was observed more frequently with increasing age, with antibiotics (34.9%) and nonsteroidal anti-inflammatory drugs (17.9%) being the most common causes. CONCLUSIONS: The most common anaphylaxis trigger in Korean children was food. Data on these triggers show that their relative frequency may vary by age.
Files in This Item:
T201603784.pdf Download
DOI
10.4168/aair.2016.8.6.535
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
Yonsei Authors
김경원(Kim, Kyung Won) ORCID logo https://orcid.org/0000-0003-4529-6135
김규언(Kim, Kyu Earn)
손명현(Sohn, Myung Hyun) ORCID logo https://orcid.org/0000-0002-2478-487X
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/152198
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