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Time and cost effective production of sodium [18F]fluoride using a dedicated automation module with disposable cassettes for GMP environment

Authors
 Jae Yong Choi  ;  Ji Woong Lee  ;  Kyo Chul Lee  ;  Kyeong Min Kim  ;  Youngbeom Seo  ;  Jung Young Kim  ;  Young Hoon Ryu 
Citation
 JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY, Vol.309(3) : 983-987, 2016 
Journal Title
 JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY 
ISSN
 0236-5731 
Issue Date
2016
Keywords
Sodium [18F]fluoride ; Bone scintigraphy ; Positron emission tomography
Abstract
The aim of the present study is to establish a time and cost effective Na[18F]F preparation method. The process is composed of absorbing radioactive impurities with cation exchange cartridge (CM), trapping 18F-fluroide with QMA cartridges, and formulating the product. The total preparation time determined at the end of bombardment was 4 min and the radiochemical yield was 82 % (n = 29). The final formulated Na[18F]F solution satisfies the USP criteria for quality control.
Full Text
https://link.springer.com/article/10.1007/s10967-016-4709-5
DOI
10.1007/s10967-016-4709-5
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학교실) > 1. Journal Papers
Yonsei Authors
Ryu, Young Hoon(유영훈) ORCID logo https://orcid.org/0000-0002-9000-5563
Choi, Jae Yong(최재용)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/152143
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