69 91

Cited 14 times in

Mechanosensory neurons control sweet sensing in Drosophila

DC FieldValueLanguage
dc.contributor.author문석준-
dc.contributor.author서정택-
dc.contributor.author정용택-
dc.date.accessioned2017-10-26T07:25:27Z-
dc.date.available2017-10-26T07:25:27Z-
dc.date.issued2016-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/152009-
dc.description.abstractAnimals discriminate nutritious food from toxic substances using their sense of taste. Since taste perception requires taste receptor cells to come into contact with water-soluble chemicals, it is a form of contact chemosensation. Concurrent with that contact, mechanosensitive cells detect the texture of food and also contribute to the regulation of feeding. Little is known, however, about the extent to which chemosensitive and mechanosensitive circuits interact. Here, we show Drosophila prefers soft food at the expense of sweetness and that this preference requires labellar mechanosensory neurons (MNs) and the mechanosensory channel Nanchung. Activation of these labellar MNs causes GABAergic inhibition of sweet-sensing gustatory receptor neurons, reducing the perceived intensity of a sweet stimulus. These findings expand our understanding of the ways different sensory modalities cooperate to shape animal behaviour.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageEnglish-
dc.publisherNature Pub. Group-
dc.relation.isPartOfNature Communications-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdolescent-
dc.subject.MESHAlleles-
dc.subject.MESHChild-
dc.subject.MESHChild, Preschool-
dc.subject.MESHCiliopathies/diagnosis-
dc.subject.MESHCiliopathies/genetics*-
dc.subject.MESHExome*-
dc.subject.MESHFemale-
dc.subject.MESHGenetic Heterogeneity-
dc.subject.MESHHumans-
dc.subject.MESHInfant-
dc.subject.MESHKidney Diseases, Cystic/diagnosis-
dc.subject.MESHKidney Diseases, Cystic/genetics*-
dc.subject.MESHMale-
dc.subject.MESHMutation-
dc.subject.MESHSequence Analysis, DNA/methods-
dc.titleMechanosensory neurons control sweet sensing in Drosophila-
dc.typeArticle-
dc.publisher.locationEngland-
dc.contributor.collegeCollege of Dentistry-
dc.contributor.departmentDept. of Oral Biology-
dc.contributor.googleauthorYong Taek Jeong-
dc.contributor.googleauthorSoo Min Oh-
dc.contributor.googleauthorJaewon Shim-
dc.contributor.googleauthorJeong Taeg Seo-
dc.contributor.googleauthorJae Young Kwon-
dc.contributor.googleauthorSeok Jun Moon-
dc.identifier.doi10.1038/ncomms12872-
dc.contributor.localIdA01905-
dc.contributor.localIdA01358-
dc.relation.journalcodeJ02293-
dc.identifier.eissn2041-1723-
dc.identifier.pmid27641708-
dc.contributor.alternativeNameMoon, Seok Jun-
dc.contributor.alternativeNameSeo, Jeong Taeg-
dc.contributor.affiliatedAuthorSeo, Jeong Taeg-
dc.contributor.affiliatedAuthorMoon, Seok Jun-
dc.citation.volume7-
dc.citation.startPage12872-
dc.identifier.bibliographicCitationNature Communications, Vol.7 : 12872, 2016-
dc.date.modified2017-10-24-
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Oral Biology (구강생물학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.