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간세포암종 환자에서 폐전이 시 폐절제술의 임상적 결과

Other Titles
 Clinical Outcome of Pulmonary Resections in Patients with Pulmonary Metastasis of Hepatocellular Carcinoma 
 김경규  ;  김자경  ;  김도영  ;  안상훈  ;  전재윤  ;  문영명  ;  정경영  ;  한광협 
 Korean Journal of Hepatology (대한간학회지), Vol.11(4) : 350-358, 2005 
Journal Title
Korean Journal of Hepatology(대한간학회지)
Issue Date
Adult ; Carcinoma, Hepatocellular/diagnosis ; Carcinoma, Hepatocellular/mortality ; Carcinoma, Hepatocellular/secondary* ; Carcinoma, Hepatocellular/surgery* ; Humans ; Liver Neoplasms/pathology* ; Lung Neoplasms/diagnosis ; Lung Neoplasms/mortality ; Lung Neoplasms/secondary* ; Lung Neoplasms/surgery* ; Male ; Middle Aged ; Neoplasm Recurrence, Local ; Pneumonectomy*/mortality ; Survival Rate ; Treatment Outcome
Background/Aims: Although the lung is the most common site of extrahepatic spread from hepatocellular carcinoma (HCC), the role of surgery for pulmonary metastasis remains unclear. The aim of this study was to evaluate the efficacy of pulmonary resection in patients with pulmonary metastasis from HCC.
Methods: Between July 2000 and July 2004, a total of 6 patients with pulmonary metastasis from HCC underwent curative pulmonary resections. The patients were divided into two groups (Surgery group and Non-surgery group) according to the primary treatment modality of HCC. Medical records, imaging studies, and pathologic reports of the surgical specimens were reviewed.
Results: Three patients in the surgery group underwent pulmonary resections for a solitary metastasis after hepatectomy for HCC, and they are all still alive. One of the 3 patients developed a tumor recurrence in the chest wall after pulmonary resection. The survival time after diagnosis of HCC were 79, 122, and 54 months, respectively. The survival time after pulmonary metastatectomy were 49, 39, and 20 months in the three patients. Another 3 patients in the non-surgery group, received a pulmonary metastatectomy; they had either a complete response HCC or partial radiologic response. These 3 patients developed recurrent disease in the liver. One of 3 patients died. The survival time after diagnosis of HCC were 153, 83, 12 months. The survival time after pulmonary metastatectomy were 51, 4, 2 months.
Conclusions: The surgical resections of a solitary pulmonary metastasis from HCC in highly selected patients might be an effective treatment modalities for prolonged survival. (Korean J Hepatol 2005;11:350-358)
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers
Yonsei Authors
Ahn, Sang Hoon(안상훈) ORCID logo https://orcid.org/0000-0002-3629-4624
Chon, Chae Yoon(전재윤)
Chung, Kyung Young(정경영)
Han, Kwang-Hyub(한광협) ORCID logo https://orcid.org/0000-0003-3960-6539
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