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Kennedy 병의 신경전도검사

Other Titles
 Nerve Conduction Studies in Kennedy’s Disease 
Authors
 조정희  ;  김승민  ;  김지현  ;  정연경  ;  강사윤  ;  이준홍  ;  선우일남 
Citation
 Journal of the Korean Association of EMG-Electrodiagnostic Medicine (대한근전도 전기진단의학회지), Vol.7(1) : 8-12, 2005 
Journal Title
 Journal of the Korean Association of EMG-Electrodiagnostic Medicine (대한근전도 전기진단의학회지) 
ISSN
 1229-6066 
Issue Date
2005
MeSH
Kennedy's disease ; Nerve conduction study
Keywords
Kennedy's disease ; Nerve conduction study
Abstract
Objectives: The aim of this study is to define the characteristics of the nerve conduction studies(NCS) in Kennedy’s disease. Methods: We reviewed the NCS of 21 patients in 18 families with genetically confirmed Kennedy’s disease. We analyzed terminal latencies(TL), nerve conduction velocities(NCV) and amplitudes of compound action potentials of the median, ulnar, peroneal, posterior tibial and sural nerves. Results: Abnormal NCS was noticed in 13(61.9%) of 21 patients ; reduced or absent sensory nerve action potentials(SNAPs) in 12(57.1%), reduced amplitudes of compound muscle action potentials(CMAPs) in 7(33.3%), slow motor or sensory NCVs in 5(23.8%) and prolonged TL in 3(14.3%). Sensory symptoms/signs were noticed only in 4 patients; 3 with abnormal sensory NCS and one with normal sensory NCS. In 4 patients with serial NCS, significant reduction of CMAPs was seen in 9 and 13 years later, but not in 2 and 3 years intervals. There was no significant change of SNAPs in these 4 cases. Conclusion: We found that the abnormal sensory NCS was common in Kennedy disease, but not essential for the diagnosis of this disease. There was no close relationship between sensory NCS and clinical findings. Follow-up NCS showed slowly progressive reduction of CMAPs but not SNAPs.
Files in This Item:
T200501490.pdf Download
DOI
OAK-2005-06384
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Seung Min(김승민) ORCID logo https://orcid.org/0000-0002-4384-9640
Sunwoo, Il Nam(선우일남)
Cho, Jeong Hee(조정희)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/151473
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