328 283

Cited 0 times in

그레이브스 병과 동반된 갑상선암

Other Titles
 Graves's Disease Presenting Concurrently with Thyroid Cancer 
Authors
 이잔디  ;  남기현  ;  임치영  ;  윤종호  ;  장항석  ;  정웅윤  ;  박정수 
Citation
 JOURNAL OF THE KOREAN SURGICAL SOCIETY , Vol.69(5) : 374-380, 2005 
Journal Title
JOURNAL OF THE KOREAN SURGICAL SOCIETY (대한외과학회지)
ISSN
 1226-0053 
Issue Date
2005
MeSH
Graves' disease ; Thyroid cancer ; Prognostic factor ; Disease-free survival rate
Keywords
Graves' disease ; Thyroid cancer ; Prognostic factor ; Disease-free survival rate
Abstract
Purpose: Graves’ disease presenting concurrently with thyroid cancer is a rare condition. The clinical behaviors and the extent of surgery in this condition is still controversial. This study examined the prognostic factors influencing the long-term outcomes as well as the appropriate treatment modalities in patients with Graves’ disease presenting concurrently with thyroid cancer. Methods: Forty nine patients who underwent surgery for thyroid cancer with Graves’ disease were enrolled in this study. The outcomes of various types of surgical treatments as well as the factors associated with the long-term outcome were retrospectively analyzed. Results: There were 42 women and 7 men with a median age 39 years (15~70 years). The surgical procedures included a bilateral subtotal thyroidectomy (n=17), a bilateral total thyroidectomy (n=16), and a total and contralateral subtotal thyroidectomy (n=16). The mean follow-up period was 83 months (4~218 months) after surgery. Disease-free survival at 5 and 10 years were 97.6% and 88.9%, respectively. Univariate log-rank survival analyses revealed that the age at diagnosis, the size of the thyroid cancer, capsular invasion, multiplicity, lymph node involvement, and clinical cancer to be poor prognostic factors. However, the extent of the surgical treatment was not significant for survival. Conclusion: The prognosis is expected to be poor when thyroid cancer presenting concurrently with Graves’ disease is clinically apparent or has invaded the thyroid capsule. Patients with Graves’ disease should be screened with ultrasonography to detect thyroid cancer. A total thyroidec-tomy or completion total thyroidectomy is not necessary in patients who do not have any of the poor prognostic factors, such as incidentally detected microcarcinoma postoperatively.
Files in This Item:
T200501317.pdf Download
DOI
OAK-2005-05942
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Nam, Kee Hyun(남기현) ORCID logo https://orcid.org/0000-0002-6852-1190
Park, Cheong Soo(박정수)
Yoon, Jong Ho(윤종호)
Lee, Jan Dee(이잔디) ORCID logo https://orcid.org/0000-0003-4090-0049
Lim, Chi Young(임치영)
Chang, Hang Seok(장항석) ORCID logo https://orcid.org/0000-0002-5162-103X
Chung, Woong Youn(정웅윤)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/151448
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links