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The relationship of the anthropometric variables to the infusion rate of rocuronium in the elderly

Authors
 Bon Nyeo Koo  ;  Sun Jun Bai  ;  Yang-Sik Shin  ;  Woo Chang Lee 
Citation
 YONSEI MEDICAL JOURNAL, Vol.46(5) : 643-647, 2005 
Journal Title
 YONSEI MEDICAL JOURNAL 
ISSN
 0513-5796 
Issue Date
2005
MeSH
Adult ; Aged ; Androstanols/administration & dosage* ; Anthropometry* ; Body Height ; Body Mass Index ; Body Surface Area ; Body Weight ; Female ; Humans ; Infusions, Intravenous ; Male ; Middle Aged ; Neuromuscular Nondepolarizing Agents/administration & dosage* ; Rocuronium ; Skinfold Thickness
Keywords
Anthropometric variables ; elderly patients ; infusion rate ; neuromuscular monitoring ; rocuronium
Abstract
We have determined the infusion rates of rocuronium in the elderly and young adult patients during sevoflurane and nitrous oxide anesthesia. The correlation of some anthropometric predictors with infusion rate of rocuronium was also investigated for both elderly and young adult. Participating patients were assigned to one of two groups: 1) young adult patients aged 20 to 50 years (n = 30); 2) elderly patients aged over 65 years (n = 30). The anthropometric variables such as height, weight, ratio of weight to body surface area, subscapularis and suprailiac skin folds, body surface area, body mass index and % ideal body weight were evaluated as predictors for infusion rate. The infusion rate in elderly patients was significantly less compared with that in young adult patients (p < 0.05). In elderly patients, no anthropometric predictor was related to the infusion rate of rocuronium. This suggests that the infusion rate of rocuronium for an elderly patient needs to be individualized by monitoring neuromuscular transmission to avoid excessive dose.
Files in This Item:
T200501282.pdf Download
DOI
10.3349/ymj.2005.46.5.643
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
Yonsei Authors
Koo, Bon-Nyeo(구본녀) ORCID logo https://orcid.org/0000-0002-3189-1673
Bai, Sun Joon(배선준) ORCID logo https://orcid.org/0000-0001-5027-3232
Shin, Yang Sik(신양식)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/151333
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