아토피피부염 환자에서 발생한 카포시수두 모양발진의 임상적 특징과 선행인자에 관한 연구

Abstract

Background: Kaposi’s varicelliform eruption(KVE) is a widespread cutaneous infection of inflamed skin with the herpes simplex virus, vaccinia or coxsackie virus most often occurring in patients with atopic dermatitis(AD).

Objective: Our purpose was to characterize the clinical features and predisposing factors of KVE in the patients with AD. Methods: A retrospective analysis of 49 AD patients with KVE seen from 2001 to 2004 was performed. We analyzed sex, age at onset of AD or KVE, medical history of other atopic diseases, extent of involvement of skin lesions of AD, distribution of KVE, treatment before development of KVE, and IgE levels.

Results: In 49 patients with KVE, 19 patients(38.8%) showed generalized distribution. Face was the most common site of involvement. The symptoms of AD were aggravated before the onset of KVE with having herbal medication or alternative therapy in 84.2% of generalized KVE. The higher the distribution rate of AD was, the more generalized the involvement of Kaposi’s varicelliform eruption was,

Conclusion: The development and distribution of KVE in AD patients are associated with the extent of involvement of skin lesions and treatment of modalities of predisposing AD.