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테트라싸이클린을 함유한 기능성 키토산 차단막의 제조
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이용근 | - |
dc.contributor.author | 최성호 | - |
dc.date.accessioned | 2017-10-26T06:47:26Z | - |
dc.date.available | 2017-10-26T06:47:26Z | - |
dc.date.issued | 2005 | - |
dc.identifier.issn | 1225-1089 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/151301 | - |
dc.description.abstract | Chitosan, a poly-saccharide, has been widely studied as bone substitution and membrane material in periodontology as well as orthopedic application. Tetracycline has been considered for use in the treatment of chronic periodontal disease and gingivitis. The aim of the present study is to make a comparative study of two ways for fabricating chitosan membrane containing tetracycline and achieve sustained and controlled local delivery of the antibiotic to the diseased tissue. Two types of membranes, non-woven and sponge, were fabricated with various concentration of tetracycline. The tensile strength of the chitosan fiber was tested by Vibrodyn and the membranes were tested on a universal test machine. Streptococcus mutans were employed to examine the antibacterial properties of the membranes. Body-safety of the membranes were determined by the Salmonella Mutagenicity test, the micronucleus test, the acute oral toxicity test, and skin patch test. The sponge type chitosan membrane was found to have an excellent tensile strength. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | Korean | - |
dc.publisher | 한국섬유공학회 | - |
dc.relation.isPartOf | Journal of the Korean Society of Textile Engineers and Chemists (한국섬유공학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 테트라싸이클린을 함유한 기능성 키토산 차단막의 제조 | - |
dc.title.alternative | Preparation of Functional Chitosan Membranes Containing Tetracycline | - |
dc.type | Article | - |
dc.publisher.location | Korea | - |
dc.contributor.college | College of Dentistry (치과대학) | - |
dc.contributor.college | College of Dentistry (치과대학) | - |
dc.contributor.department | Dept. of Dental Biomaterials and Bioengineering (치과생체재료공학교실) | - |
dc.contributor.department | Dept. of Periodontics (치주과학교실) | - |
dc.contributor.googleauthor | 장기성 | - |
dc.contributor.googleauthor | 이수복 | - |
dc.contributor.googleauthor | 이범훈 | - |
dc.contributor.googleauthor | 민우기 | - |
dc.contributor.googleauthor | 김원근 | - |
dc.contributor.googleauthor | 정용식 | - |
dc.contributor.googleauthor | 최성호 | - |
dc.contributor.googleauthor | 이용근 | - |
dc.contributor.localId | A02976 | - |
dc.contributor.localId | A04081 | - |
dc.relation.journalcode | J02960 | - |
dc.identifier.eissn | 2288-6419 | - |
dc.contributor.alternativeName | Lee, Yong Keun | - |
dc.contributor.alternativeName | Choi, Seong Ho | - |
dc.contributor.affiliatedAuthor | 이용근 | - |
dc.citation.volume | 42 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 155 | - |
dc.citation.endPage | 160 | - |
dc.identifier.bibliographicCitation | Journal of the Korean Society of Textile Engineers and Chemists (한국섬유공학회지), Vol.42(3) : 155-160, 2005 | - |
dc.date.modified | 2017-05-04 | - |
dc.identifier.rimsid | 44021 | - |
dc.type.rims | ART | - |
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