0 246

Cited 9 times in

Pretreatment levels of serum squamous cell carcinoma antigen and urine polyamines in women with squamous cell carcinoma of the cervix

Authors
 Y.T. Kim  ;  B.S. Yoon  ;  J.W. Kim  ;  S.H. Kim  ;  J.Y. Kwon  ;  J.H. Kim 
Citation
 INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, Vol.91(1) : 47-52, 2005 
Journal Title
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
ISSN
 0020-7292 
Issue Date
2005
MeSH
Adult ; Aged ; Antigens, Neoplasm/blood* ; Carcinoma, Squamous Cell/blood ; Carcinoma, Squamous Cell/metabolism* ; Carcinoma, Squamous Cell/pathology ; Carcinoma, Squamous Cell/urine ; Female ; Humans ; Lymphatic Metastasis ; Middle Aged ; Neoplasm Staging ; Polyamines/urine* ; Sensitivity and Specificity ; Serpins/blood* ; Uterine Cervical Neoplasms/blood ; Uterine Cervical Neoplasms/metabolism* ; Uterine Cervical Neoplasms/pathology ; Uterine Cervical Neoplasms/urine
Keywords
Squamous cell carcinoma antigen ; Urine polyamines ; Lymph node metastases ; Cervical cancer
Abstract
OBJECTIVES: To investigate whether pretreatment levels of serum squamous cell carcinoma antigen (SCCA) and urine polyamines can predict lymph node metastases in patients with early stage cervical carcinoma.
METHODS: Pretreatment measurement of serum SCCA and urine polyamine levels was carried out for 419 women. Of those women, 104 with stage IB and IIA cancer received radical surgery and had tumor size reassessed postoperatively.
RESULTS: The women had increased levels of serum SCCA (>2.0 ng/mL) and elevated urine polyamines (>45 micromol/g of creatinine) with advanced cancer stage (P<0.01). The median SCCA level was significantly higher in women with metastatic disease than that in those without lymph node involvement (3.9 vs. 1.1; P<0.01). Women with nodal involvement also had significantly higher median levels of urine polyamines than those without nodal disease.
CONCLUSIONS: Pretreatment measurement of SCCA and urine polyamine levels may help in predicting lymph node metastases in women with early stage cervical carcinoma.
Full Text
http://www.sciencedirect.com/science/article/pii/S0020729205003450
DOI
10.1016/j.ijgo.2005.06.010
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
Yonsei Authors
Kwon, Ja Young(권자영) ORCID logo https://orcid.org/0000-0003-3009-6325
Kim, Sung Hoon(김성훈) ORCID logo https://orcid.org/0000-0002-1645-7473
Kim, Young Tae(김영태) ORCID logo https://orcid.org/0000-0002-7347-1052
Kim, Jae Wook(김재욱)
Kim, Jae Hoon(김재훈) ORCID logo https://orcid.org/0000-0001-6599-7065
Yoon, Bo Sung(윤보성)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/151256
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links