The Amyloidosis represent a heterogeneous group of disorders characterized by abnormal extracellular and endothelial accumulation of insoluble proteins. This disorder displays variable clinical symptoms depending upon the involved organ and a diagnosis is rendered through a biopsy of the affected organ, follwed by staining using Congo-red which reveals an apple-green birefringence.
We report a case of secondary amyloidosis diagnosed incidentally by endoscopic gastric and sigmoid colon mucosal biopsy in a patient who had history of bronchiectasis and recurrent pneumonia, pseudomembranous colitis and paralytic ileus.