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면역치료로 치유된 구강 알레르기 증후군 1예

Other Titles
 A Case of Successful Immunotherapy in the Oral Allergy Syndrome 
Authors
 이근호  ;  이용원  ;  홍천수  ;  박중원 
Citation
 Journal of Asthma, Allergy and Clinical Immunology (천식 및 알레르기), Vol.25(2) : 150-152, 2005 
Journal Title
 Journal of Asthma, Allergy and Clinical Immunology (천식 및 알레르기) 
ISSN
 1226-8739 
Issue Date
2005
Abstract
Oral allergy syndrome (OAS), defined as an immediate swelling and itching sensation of mouth and throat after ingestion of fresh fruit, is commonly found in the patients with pollinosis. The high incidence of OAS is due to cross- reactivity between pollen and fruit allergens. Many recent studies show that immunotherapy (IT) with extracts of pollen can relieve symptoms of OAS. A 33 year-old female visited our clinic with the complaint of oral mucosal swelling and itching sensation after ingestion of fresh fruit (apple, pear, kiwi, banana, melon and fresh chest nut) for 13 years, with simultaneous allergic rhinitis worsening in spring and fall. In the skin prick test, she had strongly positive reaction to alder (mean wheal size 23.5 mm), oak (10.5 mm), walnut (12 mm), Japanese cedar (17 mm), bermuda (14 mm), sagebrush (8.5 mm), and Dermatophagoides farinae (17 mm). For pollens, specific IgE to alder (58.6 kU/L), oak (35.2 kU/L), walnut (9.51 kU/L), Japanese cedar (3.99 kU/L), bermuda (6.96 kU/L) and sagebrush (9.88 kU/L) have been proved by CAP-FEIA(Fluorescent Enzyme Immunoassay) (Pharmacia, Uppsala, Sweden). For fruit allergens, specific IgE to apple (13.0 kU/L), peanut (4.1 kU/L), carrot (5.9 kU/L), and pear (1.7 kU/L) have been detected but not to peach and banana. The IT with extracts of alder, oak, walnut, Japanese cedar, bermuda, sagebrush and D. farinae was started. Her allergic symptoms to pollens in spring and autumn were improved after IT. Furthermore the allergic symptoms to fruits began to disappear after initiation of IT. After 9 months of IT, she can enjoy all the fruits that provoking OAS without allergic symptoms.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
박중원(Park, Jung Won) ORCID logo https://orcid.org/0000-0003-0249-8749
이근호(Lee, Keun Ho)
이용원(Lee, Yong Won)
홍천수(Hong, Chein Soo)
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/151214
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