Cited 14 times in
Activation of monoamine oxidase isotypes by prolonged intake of aluminum in rat brain
DC Field | Value | Language |
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dc.contributor.author | 이종은 | - |
dc.date.accessioned | 2017-10-26T06:40:56Z | - |
dc.date.available | 2017-10-26T06:40:56Z | - |
dc.date.issued | 2005 | - |
dc.identifier.issn | 0162-0134 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/151165 | - |
dc.description.abstract | Rats were fed 100 μM aluminum maltolate for one year in their drinking water. Brain aluminum contents have increased 4.2-fold in the aluminum-treated group, whereas no significant changes in the body weight, brain weight, and brain protein content were observed. Long-term aluminum feeding induced apoptosis as assessed by the terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling method and showed activatory effects on the catalytic efficiency (kcat/KM) of monoamine oxidase-A and monoamine oxidase-B up to 1.9- and 3.8-fold, respectively. The expression level of monoamine oxidase isotypes on the Western blot remained unchanged between the two groups, suggesting a change in post-translational regulation of the activities of monoamine oxidase isotypes by long-term aluminum feeding. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | JOURNAL OF INORGANIC BIOCHEMISTRY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Administration, Oral | - |
dc.subject.MESH | Aluminum/administration & dosage | - |
dc.subject.MESH | Aluminum/toxicity* | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Blotting, Western | - |
dc.subject.MESH | Brain/enzymology | - |
dc.subject.MESH | Enzyme Activation | - |
dc.subject.MESH | Gene Expression Profiling | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Monoamine Oxidase/drug effects | - |
dc.subject.MESH | Monoamine Oxidase/metabolism* | - |
dc.subject.MESH | Rats | - |
dc.subject.MESH | Rats, Sprague-Dawley | - |
dc.title | Activation of monoamine oxidase isotypes by prolonged intake of aluminum in rat brain | - |
dc.type | Article | - |
dc.publisher.location | United States | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anatomy (해부학교실) | - |
dc.contributor.googleauthor | Jae-Wan Huh | - |
dc.contributor.googleauthor | Myung-Min Choi | - |
dc.contributor.googleauthor | Jang Han Lee | - |
dc.contributor.googleauthor | Seung-Ju Yang | - |
dc.contributor.googleauthor | Mi Jung Kim | - |
dc.contributor.googleauthor | Jene Choi | - |
dc.contributor.googleauthor | Kwan Ho Lee | - |
dc.contributor.googleauthor | Jong Eun Lee | - |
dc.contributor.googleauthor | Sung-Woo Cho | - |
dc.identifier.doi | 10.1016/j.jinorgbio.2005.06.032 | - |
dc.contributor.localId | A03146 | - |
dc.relation.journalcode | J01459 | - |
dc.identifier.eissn | 1873-3344 | - |
dc.identifier.pmid | 16087240 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0162013405001960 | - |
dc.subject.keyword | Aluminum | - |
dc.subject.keyword | Monoamine oxidase | - |
dc.subject.keyword | Apoptosis | - |
dc.subject.keyword | Neurodegeneration | - |
dc.contributor.alternativeName | Lee, Jong Eun | - |
dc.citation.volume | 99 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 2088 | - |
dc.citation.endPage | 2091 | - |
dc.identifier.bibliographicCitation | JOURNAL OF INORGANIC BIOCHEMISTRY, Vol.99(10) : 2088-2091, 2005 | - |
dc.date.modified | 2017-05-04 | - |
dc.identifier.rimsid | 43500 | - |
dc.type.rims | ART | - |
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