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Characteristics of Type 2 Diabetes in Terms of Insulin Resistance in Korea

Other Titles
 Characteristics of Type 2 Diabetes in Terms of Insulin Resistance in Korea 
Authors
 Jong-Suk Park  ;  Chul-Sik Kim  ;  Joo-Young Nam  ;  Dol-Mi Kim  ;  Min-Ho Jo  ;  Jina Park  ;  Chul-Woo Ahn  ;  Bong-Soo Cha  ;  Sung-Kil Lim  ;  Kyung-Rae Kim  ;  Hyun-Chul Lee  ;  Kap-Bum Huh 
Citation
 Yonsei Medical Journal, Vol.46(4) : 484-490, 2005 
Journal Title
 Yonsei Medical Journal 
ISSN
 0513-5796 
Issue Date
2005
Abstract
The aim of this study was to assess the implications of insulin resistance on the clinical and biochemical profiles of Korean type 2 diabetic patients. 122 patients with type 2 diabetes underwent a short insulin tolerance test to assess insulin resistance. Subjects were classified in tertiles according to ISI (insulin sensitivity index), and the tertile I (the insulin-resistant group) and tertile III (the insulin-sensitive group) clinical and biochemical parameters were compared. Age, waist circumference (WC), systolic blood pressure (SBP), HbA1c, body fat content, and fasting plasma glucose were significantly higher in tertile I than tertile III (all p < 0.05). The frequency of hypertension and family history of cerebrovascular disease (CVD) were greater in tertile I than III (p < 0.05). To evaluate the factors affecting ISI, multiple regression was performed, and age, WC, SBP, HbA1c, and body fat content were found to be independently related to insulin resistance (p < 0.05). Old age, hypertension, central obesity, and poor glycemic control were identified as clinical parameters of insulin resistance in Korean type 2 diabetic patients.
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DOI
10.3349/ymj.2005.46.4.484
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실)
Yonsei Authors
김경래(Kim, Kyung Rae)
김똘미(Kim, Dol Mi)
김철식(Kim, Chul Sik)
남주영(Nam, Ju Young)
박종석(Park, Jong Suk)
박진아(Park, Jina)
안철우(Ahn, Chul Woo)
이현철(Lee, Hyun Chul)
임승길(Lim, Sung Kil)
차봉수(Cha, Bong Soo) ORCID logo https://orcid.org/0000-0003-0542-2854
허갑범(Huh, Kap Bum)
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/151147
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