51 167

Cited 1 times in

Characteristics of Type 2 Diabetes in Terms of Insulin Resistance in Korea

 Jong-Suk Park  ;  Chul-Sik Kim  ;  Joo-Young Nam  ;  Dol-Mi Kim  ;  Min-Ho Jo  ;  Jina Park  ;  Chul-Woo Ahn  ;  Bong-Soo Cha  ;  Sung-Kil Lim  ;  Kyung-Rae Kim  ;  Hyun-Chul Lee  ;  Kap-Bum Huh 
 YONSEI MEDICAL JOURNAL, Vol.46(4) : 484-490, 2005 
Journal Title
Issue Date
Adult ; Aged ; Blood Glucose/analysis ; C-Peptide/analysis ; Cholesterol, HDL/blood ; Diabetes Mellitus, Type 2/metabolism* ; Female ; Glycated Hemoglobin A/analysis ; Humans ; Insulin Resistance* ; Male ; Middle Aged
Insulin resistance ; type 2 diabetes ; Korea
The aim of this study was to assess the implications of insulin resistance on the clinical and biochemical profiles of Korean type 2 diabetic patients. 122 patients with type 2 diabetes underwent a short insulin tolerance test to assess insulin resistance. Subjects were classified in tertiles according to ISI (insulin sensitivity index), and the tertile I (the insulin-resistant group) and tertile III (the insulin-sensitive group) clinical and biochemical parameters were compared. Age, waist circumference (WC), systolic blood pressure (SBP), HbA1c, body fat content, and fasting plasma glucose were significantly higher in tertile I than tertile III (all p < 0.05). The frequency of hypertension and family history of cerebrovascular disease (CVD) were greater in tertile I than III (p < 0.05). To evaluate the factors affecting ISI, multiple regression was performed, and age, WC, SBP, HbA1c, and body fat content were found to be independently related to insulin resistance (p < 0.05). Old age, hypertension, central obesity, and poor glycemic control were identified as clinical parameters of insulin resistance in Korean type 2 diabetic patients.
Files in This Item:
T200500997.pdf Download
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Kyung Rae(김경래)
Kim, Dol Mi(김똘미)
Kim, Chul Sik(김철식)
Nam, Ju Young(남주영)
Park, Jong Suk(박종석)
Park, Jina(박진아)
Ahn, Chul Woo(안철우) ORCID logo https://orcid.org/0000-0003-3733-7486
Lee, Hyun Chul(이현철)
Lim, Sung Kil(임승길)
Cha, Bong Soo(차봉수) ORCID logo https://orcid.org/0000-0003-0542-2854
Huh, Kap Bum(허갑범)
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.