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Development of Korean Standard Brain Templates

Authors
 Jae Sung Lee  ;  Dong Soo Lee  ;  Jinsu Kim  ;  Yu Kyeong Kim  ;  Eunjoo Kang  ;  Hyejin Kang  ;  Keon Wook Kang  ;  Jong Min Lee  ;  Jae-Jin Kim  ;  Hae-Jeong Park  ;  Jun Soo Kwon  ;  Sun I. Kim  ;  Tae Woo Yoo  ;  Kee-Hyun Chang  ;  Myung Chul Lee 
Citation
 JOURNAL OF KOREAN MEDICAL SCIENCE, Vol.20(3) : 483-488, 2005 
Journal Title
 JOURNAL OF KOREAN MEDICAL SCIENCE 
ISSN
 1011-8934 
Issue Date
2005
MeSH
Adolescent ; Adult ; Age Factors ; Aged ; Brain/diagnostic imaging* ; Female ; Fluorodeoxyglucose F18 ; Humans ; Korea ; Magnetic Resonance Imaging/methods ; Male ; Middle Aged ; Positron-Emission Tomography/methods ; Radiography ; Sex Factors
Keywords
Brain ; Magnetic Resonance Imaging ; Positron-Emission Tomography ; Atlases ; Reference Standards
Abstract
We developed age, gender and ethnic specific brain templates based on MR and Positron-Emission Tomography (PET) images of Korean normal volunteers. Seventy-eight normal right-handed volunteers (M/F=49/29) underwent 3D T1-weighted SPGR MR and F-18-FDG PET scans. For the generation of standard templates, an optimal target brain that has the average global hemispheric shape was selected for each gender. MR images were then spatially normalized by linear transformation to the target brains, and normalization parameters were reapplied to PET images. Subjects were subdivided into 2 groups for each gender: the young/midlife (<55 yr) and the elderly groups. Young and elderly MRI/PET templates were composed by averaging the spatially normalized images. Korean templates showed different shapes and sizes (mean length, width, and height of the brains were 16.5, 14.3 and 12.1 cm for man, and 15.6, 13.5 and 11.4 cm for woman) from the template based on Caucasian (18.3, 14.2, and 13.3 cm). MRI and PET templates developed in this study will provide the framework for more accurate stereotactic standardization and anatomical localization.
Files in This Item:
T200500892.pdf Download
DOI
10.3346/jkms.2005.20.3.483
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학교실) > 1. Journal Papers
Yonsei Authors
Park, Hae Jeong(박해정) ORCID logo https://orcid.org/0000-0002-4633-0756
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/151123
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