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육아종성 유방염의 임상 및 병리학적 특성

Other Titles
 Clinicopathologic Features of Granulomatous Mastitis 
Authors
 김의정  ;  최윤정  ;  김지영  ;  김희정  ;  박양순  ;  홍순원  ;  박찬일  ;  김도일  ;  이희대  ;  정우희 
Citation
 KOREAN JOURNAL OF PATHOLOGY , Vol.39(3) : 181-186, 2005 
Journal Title
 KOREAN JOURNAL OF PATHOLOGY 
ISSN
 1738-1843 
Issue Date
2005
MeSH
Granuloma ; Mastitis ; Tuberculosis ; Corynebacterium ; Polymerase chain reaction
Keywords
Granuloma ; Mastitis ; Tuberculosis ; Corynebacterium ; Polymerase chain reaction
Abstract
Background: Granulomatous mastitis (GM) is a rare chronic inflammatory condition that clinically mimics a carcinoma. The diagnosis of idiopathic GM depends on the exclusion of other granulomatous inflammations. The purpose of this study is to correlate the clinicopathological features of GM with etiologies. Methods: We reviewed the clinical records of 58 cases that were histologically diagnosed as GM. We performed special stains for microorganisms such as Ziehl-Neelsen, periodic acid Schiff and gram stains, and polymerase chain reaction (PCR) for Mycobacterium tuberculosis (TB PCR). Results: The mean age of patients was 35.3 years. Most patients were parous except three. Seven patients (12.1%) were related with pregnancy or lactation. TB PCR was positive in nine patients (15.5%). Five patients (8.6%) had gram positive bacilli that were recognizable as coryneform bacteria. Culture study demonstrated Staphylococcus aureus in only one case. Infectious GM had a greater tendency to form abscesses. Fat necrosis was more likely to be present in idiopathic GM, but other histological features were similar to each other. Twenty-two cases (37.9%) showed recurrence. Conclusions: We suggest that TB PCR and gram stain are essential tests for the differential diagnosis of GM, because the histologic features considerably overlap irrespective of the various etiologies.
Files in This Item:
T200500606.pdf Download
DOI
OAK-2005-03863
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Park, Chan Il(박찬일)
Lee, Hy De(이희대)
Jung, Woo Hee(정우희)
Hong, Soon Won(홍순원) ORCID logo https://orcid.org/0000-0002-0324-2414
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/150461
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