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Clinical Features of Chronic Pancreatitis in Korea : A Multicenter Nationwide Study

Authors
 Ryu J.K.  ;  Lee J.K.  ;  Kim Y.T.  ;  Lee D.K.  ;  Seo D.W.  ;  Lee K.T.  ;  Kim H.G.  ;  Kim J.S.  ;  Lee H.S.  ;  Kim T.N.  ;  Rho M.H.  ;  Moon J.H.  ;  Lee J.  ;  Choi H.S.  ;  Lee W.J.  ;  Yoo B.M.  ;  Yoon Y.B. 
Citation
 DIGESTION, Vol.72(4) : 207-211, 2005 
Journal Title
DIGESTION
ISSN
 0012-2823 
Issue Date
2005
MeSH
Age Distribution ; Aged ; Alcohol Drinking/epidemiology ; Female ; Humans ; Incidence ; Korea/epidemiology ; Male ; Middle Aged ; Pancreatitis, Chronic/diagnosis* ; Pancreatitis, Chronic/epidemiology ; Pancreatitis, Chronic/etiology ; Retrospective Studies ; Risk Factors ; Sex Distribution
Keywords
Chronic pancreatitis ; Chronic pancreatitis, etiology ; Chronic pancreatitis, Korean multicenter study ; Pancreatic cancer
Abstract
BACKGROUND/AIMS: No reliable nationwide clinical data about chronic pancreatitis (CP) was available in Korea. The etiology and clinical features of CP were investigated using a multicenter nationwide study.
METHODS: 814 cases of CP were enrolled retrospectively over the past 4 years at 13 hospitals. The following data were obtained from all patients: etiology, symptoms, complications, and surgery.
RESULT: Alcohol (64.3%) was the major cause of CP and idiopathic CP (20.8%) was the second most common form. Mean patient age was 50.6 years and the male:female ratio was 6:1 (24:1 for alcoholic CP vs. 2:1 in idiopathic CP, p < 0.001). Diabetes (31.6%), pseudocysts (28.4%), biliary stricture (13.9%), and pancreatic ascites (6.6%) were the main complications. Of these, diabetes (35 vs. 26%) and pseudocyst (33.7 vs. 21.9%) were more frequent in alcoholic than in idiopathic CP. Pancreatic cancer developed in 25 patients (3.1%) during follow-up and their mean age was 59.1 years.
CONCLUSIONS: In Korea, alcohol is the most common etiology of CP. Moreover, diabetes and pseudocysts are frequent complications, especially in alcoholic CP, and pancreatic cancer development is not infrequent.
Full Text
http://www.karger.com/Article/FullText/89414
DOI
10.1159/000089414
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Dong Ki(이동기) ORCID logo https://orcid.org/0000-0002-0048-9112
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/149961
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