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StageⅡ 담낭암의 근치적 절제술 후 재발 양상과 재발 위험 요소

Other Titles
 Recurrence Patterns and Risk Factors after Curative Resection in Stage II Gallbladder Carcinoma 
 박준성  ;  윤동섭  ;  김경식  ;  최진섭  ;  이우정  ;  지훈상  ;  김병로 
 Korean Journal of Hepato-Biliary-Pancreatic Surgery, Vol.9(4) : 221-224, 2005 
Journal Title
Korean Journal of Hepato-Biliary-Pancreatic Surgery(한국간담췌외과학회지)
Issue Date
Gallbladder ; Neoplasms ; Recurrence
Gallbladder ; Neoplasms ; Recurrence
Purpose: Despite the advances in hepatobiliary imaging techniques, most patients with a gall bladder carcinoma are diagnosed at an advanced stage, with a very poor prognosis. Recent studies have shown that aggressive radical resection for an advanced stage gallbladder carcinoma can give an acceptable prognosis. However, recurrence frequently remains the main problem after a curative resection of an advanced stage gallbladder carcinoma. The aim of this study was to identify the patterns of recurrence and factors affecting recurrence after a curative resection for a stage II gallbladder carcinoma.
Methods: Between January 1991 and December 2003, 100 patients received a radical curative resection for a gallbladder carcinoma at the Yonsei University Medical Center. Of these, 77 were defined with a stage II gallbladder carcinoma according to the UICC classification (6th edition). Of the 77 patients, 67 were reviewed, and the predictors of tumor recurrence analyzed.
Results: Among the 67 patients, 38 (56.7%) suffered a recurrence. The mean length to the recurrence was 21.1 months (± 26.7 months), with the most common site being the intra- abdominal organs: liver and aortocaval lymph nodes. Infiltrating and poorly differentiated types were identified as independent prognostic factors of a recurrence after a curative resection for a stage II gallbladder carcinoma.
Conclusion: In conclusion, as a higher probability of recurrence is anticipated in cases of infiltrating and poorly differentiated types of tumor support the need for the developmentof an effective postoperative adjuvant modality for this high risk group of patients.
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1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Kyung Sik(김경식) ORCID logo https://orcid.org/0000-0001-9498-284X
Kim, Byong Ro(김병로)
Park, Joon Seong(박준성) ORCID logo https://orcid.org/0000-0001-8048-9990
Yoon, Dong Sup(윤동섭) ORCID logo https://orcid.org/0000-0001-6444-9606
Lee, Woo Jung(이우정) ORCID logo https://orcid.org/0000-0001-9273-261X
Chi, Hoon Sang(지훈상)
Choi, Jin Sub(최진섭)
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