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예후결정인자를 고려한 갑상선 미소암(微小癌)의 임상상

Other Titles
 Clinical characteristics of thyroid microcarcinomas with special reference to the prognostic factors 
 이준호  ;  이시훈  ;  이유미  ;  안철우  ;  차봉수  ;  김경래  ;  이현철  ;  김승일  ;  박정수  ;  임승길 
 Korean Journal of Medicine (대한내과학회지), Vol.69(5) : 503-509, 2005 
Journal Title
 Korean Journal of Medicine (대한내과학회지) 
Issue Date
Thyroid neoplasms ; Papillary carcinoma ; Microcarcinoma ; Prognosis
Thyroid neoplasms ; Papillary carcinoma ; Microcarcinoma ; Prognosis
Background : The incidence of thyroid microcarcinoma is increasing due to the more frequent use and improvement of ultrasonography and fine-needle aspiration biopsy. There are several prognostic factors for thyroid carcinomas. The patient`s sex, age at diagnosis, muliplicity or bilaterality of tumor masses, extrathyroidal extensions, lymph node metastasis, and presence of distant metastases are considered the most important. Since the recent update of the TNM (Tumor, Node, Metastasis) staging system, the importance of lymph node metastasis is increased. There are, however, a paucity of studies on thyroid microcarcinomas in the Korean population. Methods : We reviewed and analyzed the records of 302 patients diagnosed with, and treated for, thyroid microcarcinomas from January through December 2004. Results : 302 (50.2%) out of the 601 cases of thyroid cancers were microcarcinomas. Women comprised 275 (91.1%) of these cases. Eighty cases (26.5%) contained multiple tumor masses (>2), and 50 (16.6%) cases exhibited bilaterality. Evaluation of the histology revealed that nearly all of the cases (300 of 302) were of the papillary type. There was only one case each of the follicular and medullary histological type. There were 85 (28.1%) cases of extrathyroidal extensions, and 91 cases (30.1%) of lymph node metastasis, but no cases of distant metastases. Conclusions : Thyroid microcarcinomas have bad prognostic factors and appear to exist at relatively higher cancer stages. Therefore, it is important to treat them as early and as vigorously as possible with extensive surgery, radioactive iodine therapy, and thyroxine suppression.
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Kyung Rae(김경래)
Kim, Seung Il(김승일)
Park, Cheong Soo(박정수)
Ahn, Chul Woo(안철우) ORCID logo https://orcid.org/0000-0003-3733-7486
Rhee, Yumie(이유미) ORCID logo https://orcid.org/0000-0003-4227-5638
Lee, Hyun Chul(이현철)
Lim, Sung Kil(임승길)
Cha, Bong Soo(차봉수) ORCID logo https://orcid.org/0000-0003-0542-2854
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