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사지에 발생한 편평세포 상피암의 치료

Other Titles
 Treatment of Squamous Cell Carcinoma in Extremity 
Authors
 이두형  ;  신규호  ;  이수현  ;  한수봉 
Citation
 Journal of the Korean Bone and Joint Tumor Society (대한골관절종양학회지), Vol.11(2) : 126-133, 2005 
Journal Title
Journal of the Korean Bone and Joint Tumor Society(대한골관절종양학회지)
ISSN
 1226-4962 
Issue Date
2005
MeSH
Squamous cell carcinoma ; Burn ; Osteomyelitis ; Marjolin ulcer ; Wide excision
Keywords
Squamous cell carcinoma ; Burn ; Osteomyelitis ; Marjolin ulcer ; Wide excision
Abstract
Purpose: to know the treatment result of squamous cell carcinoma in extremity had poor prognosis with risk factor including burn scar and chronic osteomyelitis.

Material and Methods: Between Octorber 1993 and September 2002, 20 patients with squamous cell carcinoma in extremity had no distant metastasis was got operation and followed over 36 months. Amputation was done when it was hard to get enough wide margin or neurovascular structure was involved instead of wide excision. Mean age of patients was 57.2 years old and male to female was 16 to 4. TMN staging and histologic grading were performed.

Results: There were 6 metastasis (30%) in 20 cases for mean 48.3 months (36-84 months). 3 metastasis to local lymph node and 3 distant metastasis were happened at lung (in 3 cases) and thorasic vertebra (in 1 case). Survival was 18 cases at last look. 5-year survival rate was 50%. 3 local recurrence was developed at average 11 months (4-18 months). Complication was focal skin defect after wide excision and skin graft in 2 cases. The patients by wide excision got average 1.9 time operation and by amputation got average 1.3 time.

Conclusion: Squamous cell carcinoma at extremity in Korea had high metastasis rate due to burn scar and chronic osteomyelitis, and it showed equal treatment result which treated by wide excision compared with amputation.
Files in This Item:
T200501619.pdf Download
DOI
OAK-2005-06681
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Orthopedic Surgery (정형외과학교실) > 1. Journal Papers
Yonsei Authors
Shin, Kyoo Ho(신규호)
Hahn, Soo Bong(한수봉)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/149876
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