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The change of anterior segment parameters after cataract surgery using swept-source optical coherence tomography in patients with normal-tension glaucoma

Other Titles
 전안부 단층촬영을 이용한 녹내장환자에서의 백내장 수술 전 후 내안각의 지표변화 연구 
Issue Date
Dept. of Medicine/석사
Purpose : To investigate the change of anterior angle morphology and intraocular pressure (IOP) reduction after cataract surgery in patients with normal-tension glaucoma (NTG) using swept-source optical coherence tomography (SS-OCT).

Design : Prospective, comparative, observational study.

Methods : Group 1 was the control group that included normal subjects except for cataracts (“cataract group”). Group 2 was the “normal-tension glaucoma group (NTG group)” diagnosed with NTG with cataracts. Sixty-four eyes of 64 patients (group 1) and 42 eyes of 42 patients (group 2) were treated with phacoemulsification and intraocular lens implantation. Before surgery and on postoperative day 1, week 1, and month 1, the anterior chamber angles were evaluated by SS-OCT under dark conditions using the three-dimensional angle analysis scan protocol. Angle opening distance (AOD), angle recess area (ARA), trabecular-iris surface area (TISA), and trabecular-iris angle (TIA) were calculated automatically by SS-OCT after the observer marked the scleral spurs.

Results : A total of 106 patients (54 male and 52 female) were enrolled in the study. Angle parameters, AOD, TISA, and TIA were significantly increased after surgery in both groups. However, changes of angle parameters were significant in group 2. Preoperative IOP was 13.19±2.85 mmHg and postoperative IOP at 1 month was 10.46±2.96 mmHg in group 2. Preoperative IOP was 12.37±2.81 mmHg and postoperative IOP was 11.63±2.48 mmHg in group 1. After cataract surgery, the IOP was significantly reduced in group 2 (P<0.001).

Conclusions : Patients that underwent cataract surgery have improved anterior chamber angle parameters and decreased IOP.
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1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 2. Thesis
Yonsei Authors
Lee, Wonseok(이원석)
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