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Ridge regeneration of damaged extraction sockets using rhBMP-2 : an experimental study in canine
DC Field | Value | Language |
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dc.contributor.author | 정재숙 | - |
dc.date.accessioned | 2017-07-11T16:10:20Z | - |
dc.date.available | 2017-07-11T16:10:20Z | - |
dc.date.issued | 2016 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/149120 | - |
dc.description | Dept. of Dentistry/박사 | - |
dc.description.abstract | Objective: This study evaluated the dimensional ridge alteration in a buccal-bone-deficient extraction socket, and ridge regeneration following socket grafting accompanied by recombinant human bone morphogenetic protein 2 (rhBMP-2) or a collagen membrane covering. Materials and methods: In five beagle dogs, entire buccal bone of the extracted sockets of premolars was surgically removed and immediately grafted using one of the following graft protocols: (1) sham surgery without any grafting, and grafting with (2) deproteinized bovine bone mineral (DBBM), (3) DBBM/rhBMP-2 and (4) DBBM covered with a collagen membrane (DBBM/Membrane). Quantitative/ qualitative analyses were performed radiographically/histologically after 8 weeks. Results: Buccal-deficient extraction sockets healed with significant reduction in buccolingual dimension along the entire length of the socket, but all grafting techniques reduced the dimensional changes compared to the non-grafted control sites. Histologically, sites received DBBM only exhibited minimal regeneration, whereas sites grafted with DBBM/rhBMP-2 or DBBM/Membrane exhibited greater new bone formation extending the entire augmented area. Conclusion: Buccal-bone-deficiency may lead to significant volume reduction after tooth extraction along the entire length of the socket, and socket grafting accompanied by rhBMP-2 or covered with a membrane can be candidate therapies for preservation of the buccolingual dimension and successful ridge regeneration. | - |
dc.description.statementOfResponsibility | open | - |
dc.publisher | Graduate School, Yonsei University | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Ridge regeneration of damaged extraction sockets using rhBMP-2 : an experimental study in canine | - |
dc.title.alternative | 손상된 발치와에서 rhBMP-2를 이용한 치조제 재생술 | - |
dc.type | Thesis | - |
dc.contributor.alternativeName | Jung, Jae-Suk | - |
dc.type.local | Dissertation | - |
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