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Prevalence and characteristics of unruptured cerebral aneurysms in ischemic stroke patients

Other Titles
 허혈성 뇌졸중 환자에서 비파열 대뇌 동맥류의 빈도와 특성 
Authors
 김지화 
Department
 Dept. of Neurology (신경과학교실) 
Issue Date
2015
Description
의과대학/석사
Abstract
Introduction: The prevalence of unruptured cerebral aneurysms (UCAs) in ischemic stroke patients has not been investigated. We aimed to measure the prevalence and characteristics of UCAs in acute ischemic stroke (AIS) and to compare it with general population. And we evaluated factors associated with cerebral aneurysm in ischemic stroke patients.



Materials and Methods: We retrospectively reviewed brain magnetic resonance angiography (MRA) of 955 patients with AIS, and 2118 controls who had taken brain MRA as part of a health check-up. We investigated the prevalence, size, location and risk factors of the subject for UCAs.



Results: UCAs were found in 74 patients with AIS (7.7%) and in 79 people for health check-up (3.7%). Prevalence of UCAs was high in AIS group than health check-up (OR 2.17, 95% CI 1.56-3.01, p < 0.001), especially in the age of 7th decade. The mean diameter of the aneurysms was larger in AIS group than health check-up group (3.95 mm vs 3.10 mm, p = 0.010). The UCAs were mostly located in the internal carotid artery and there were no significant differences in distribution pattern between groups. Multivariate analysis showed that only previous hypertension (p = 0.028) correlated with the increased prevalence of UCAs in stroke patients.



Conclusion: This study showed higher prevalence and larger size of UCAs in AIS patients than in general population. Hypertension was associated coexistence of cerebral aneurysm and ischemic stroke.
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 2. Thesis
Yonsei Authors
Kim, Ji Hwa(김지화)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/148642
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