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알쯔하이머치매 환자에서 삶의 질의 예측인자

Other Titles
 Predictors of Quality of Life in Patients with Dementia of the Alzheimer’s Type 
Authors
 전진숙  ;  조웅  ;  오병훈 
Citation
 Journal of Korean Geriatric Psychiatry (노인정신의학), Vol.9(1) : 63-69, 2005 
Journal Title
 Journal of Korean Geriatric Psychiatry (노인정신의학) 
ISSN
 1226-6329 
Issue Date
2005
MeSH
Dementia ; Quality of life ; Age ; Cognitive function ; Severity of dementia ; Activities of daily living ; Depression ; Homocysteine
Keywords
Dementia ; Quality of life ; Age ; Cognitive function ; Severity of dementia ; Activities of daily living ; Depression ; Homocysteine
Abstract
Objectives:The aim of this study was to analyze factors affecting quality of life (QOL) among Korean dementia patients. Methods:The subjects were consisted with 54 patients with dementia of the Alzheimer's type and 54 normal aged controls with age over 60. The QOLs were assessed with the Korean Version of the Quality of Life in Alzheimer's Disease:Patient and Caregiver Report (KQOL-AD). For analyzing factors affecting QOL in dementia, the clinical data were obtained by structured interview and medical records, serum homocysteine levels were measured, and the severity of dementia (Mini-Mental State Examination, Clinical Dementia Rating, Global Deterioration Scale), functional activities (Activities of Daily Living, Instrumental Activities of Daily Living) and depression (Geriatric Depression Scale) were evaluated using various rating scales. Results:1) The mean (±S.D.) score of KQOL-AD in patients with dementia of the Alzheimer's type (24.30±5.06) was significantly (p<0.005) lower than those in normal aged controls (26.56±3.25). 2) The factors influencing on KQOL-AD in patients with dementia of the Alzheimer's type were age (p<0.01), cognitive function (p<0.01), severity of dementia (p<0.01), activities of daily living (p<0.01), depression (p<0.01) and serum homocysteine levels (p<0.05). Conclusion:In conclusion, multiple factors including problems originated from dementia itself as well as causes fundamentally related with pathophysiology of dementia might influence on the quality of life in patients with the Alzheimer's dementia.
Full Text
http://scholar.dkyobobook.co.kr/searchDetail.laf?barcode=4010023185152
DOI
OAK-2005-03346
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers
Yonsei Authors
Oh, Byong Hoon(오병훈)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/147609
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