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Body mass index and incident ischemic heart disease in South Korean men and women

Authors
 Sun Ha Jee  ;  Roberto Pastor-Barriuso  ;  Lawrence J. Appel  ;  Il Suh  ;  Edgar R. Miller III  ;  Eliseo Guallar 
Citation
 AMERICAN JOURNAL OF EPIDEMIOLOGY, Vol.162(1) : 42-48, 2005 
Journal Title
AMERICAN JOURNAL OF EPIDEMIOLOGY
ISSN
 0002-9262 
Issue Date
2005
MeSH
Adult ; Asian Continental Ancestry Group ; Body Mass Index* ; Cohort Studies ; Confidence Intervals ; Female ; Humans ; Korea/epidemiology ; Male ; Middle Aged ; Myocardial Ischemia/epidemiology* ; Myocardial Ischemia/physiopathology ; Obesity ; Proportional Hazards Models
Keywords
Asian continental ancestry group ; body mass index ; body weight ; myocardial ischemia ; obesity
Abstract
Asian populations have a higher body fat percentage for a given body mass index (BMI) than Caucasians. However, little information is available on the association of BMI with ischemic heart disease (IHD) incidence in Asians at low BMI levels. The authors prospectively evaluated the association of BMI (weight (kg)/height m2) with IHD incidence over 9 years of follow-up (1993-2001) among 133,740 South Korean adults (89,050 men, 44,690 women) who participated in the 1990 and 1992 examinations of the Korea Medical Insurance Corporation Study. Average BMI at baseline was 23.4 (standard deviation, 2.3) in men and 22.3 (standard deviation, 2.3) in women. After multivariate adjustment, there was a 14% (95% confidence interval: 12, 16) increased risk of incident IHD per unit of increase in BMI. This trend was also observed within the range considered normal by Western standards, and a BMI of 24-<25 was associated with an IHD hazard ratio of 2.01 (95% confidence interval: 1.32, 3.05) in comparison with a BMI of 18-<19. The association of BMI with IHD in this cohort of relatively young South Korean men and women was progressive over the range of BMI values, with no threshold of change in risk and no indication of a U-shaped relation at low BMI levels.
Files in This Item:
T200500298.pdf Download
DOI
10.1093/aje/kwi166
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Preventive Medicine (예방의학교실) > 1. Journal Papers
4. Graduate School of Public Health (보건대학원) > Graduate School of Public Health (보건대학원) > 1. Journal Papers
Yonsei Authors
Suh, Il(서일) ORCID logo https://orcid.org/0000-0002-9689-7849
Jee, Sun Ha(지선하) ORCID logo https://orcid.org/0000-0001-9519-3068
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/147544
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