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동시 항암화학방사선 지료를 받은 자궁경부암 환자에서 squamous cell carcinoma antigen과 예후와의 상관관계

Other Titles
 Correlation between SCC antigen and the prognosis of cervical cancer patients following concurrent chemoradiotherapy 
Authors
 박수현  ;  김영태  ;  김재욱  ;  김재훈  ;  김성훈  ;  윤보성  ;  김상운 
Citation
 Korean Journal of Gynecologic Oncology (부인종양), Vol.16(2) : 123-132, 2005 
Journal Title
Korean Journal of Gynecologic Oncology(부인종양)
ISSN
 1738-6544 
Issue Date
2005
MeSH
SCC antigen ; Cervix cancer ; concurrent chemoradiotherapy ; prognosis
Keywords
SCC antigen ; Cervix cancer ; concurrent chemoradiotherapy ; prognosis
Abstract
OBJECTIVE: The aim of this study was to determine the correlation between SCC Ag and the prognosis in cervical cancer patients following concurrent chemoradiotherapy (CCRT).
METHODS: The charts of 116 patients following concurrent chemoradiotherapy among 330 patients diagnosed to cervical cancer at Yonsei University Medical Center from Jan. 1998 to June 2003 were reviewed retrospectively. Clinical characteristics (age, parity, body mass index), stage, lesion size, cell type, squamous cell subtype, initial SCC Ag (<1.5 and >or=1.5), posttreatment SCC Ag (<1.5 and >or=1.5) was evaluated with overall survival. Distribution of SCC Ag level before CCRT in relation to FIGO stage and failure pattern in SCC positive patients before CCRT were reviewed. Overall survival was estimated according to respectively, subgroups of initial SCC Ag, SCC Ag after 2nd CCRT and posttreatment SCC Ag. Chi square test and Kaplan Meier test were used for statistical analysis (P<0.05).
RESULTS: Overall survival was significantly correlated with only stage (P=0.0014). Two patients (15.4%) among 13 patients with recurrence had SCC Ag<1.5. Subgroups (1.5CONCLUSION: The measurements of the levels of initial SCC Ag, SCC Ag after 2nd CCRT and posttreatment SCC Ag are expected to be useful in predicting the prognosis of the patients with cervical cancer.
Full Text
http://kiss.kstudy.com/journal/thesis_name.asp?tname=kiss2002&key=2440803
DOI
OAK-2005-02918
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Sang Wun(김상운) ORCID logo https://orcid.org/0000-0002-8342-8701
Kim, Sung Hoon(김성훈) ORCID logo https://orcid.org/0000-0002-1645-7473
Kim, Young Tae(김영태) ORCID logo https://orcid.org/0000-0002-7347-1052
Kim, Jae Wook(김재욱)
Kim, Jae Hoon(김재훈) ORCID logo https://orcid.org/0000-0001-6599-7065
Yoon, Bo Sung(윤보성)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/147469
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