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임신 중 동반된 급성 림프구성 백혈병 1예

Other Titles
 A case of acute Lymphocytic Leukemia in pregnancy 
Authors
 최현정  ;  박용원  ;  정준원  ;  민유홍  ;  권자영  ;  권한성  ;  김영한  ;  김성훈 
Citation
 Korean Journal of Obstetrics and Gynecology (대한산부인과학회지), Vol.48(2) : 467-472, 2005 
Journal Title
 Korean Journal of Obstetrics and Gynecology (대한산부인과학회지) 
ISSN
 1738-5628 
Issue Date
2005
MeSH
Acute lymphocytic leukemia
Keywords
Acute lymphocytic leukemia
Abstract
The incidence of acute leukemia in pregnancy is estimated to be about 1 per 75000 pregnancies, and the incidence of lymphocytic leukemia is known to be lower than myelocytic leukemia. Pregnancy dose not affect the course of acute leukemia, but thrombocytopenia, anemia and leukopenia resulting from leukemia may lead to hemorrhage, infection, and insufficient supply of oxygen and nutrition to fetus. The most important factor for chemotherapy is gestational age. Since no evidence on adverse effect of chemotherapeutic agents on fetus when given after the first trimester, aggressive chemotherapy is recommended during pregnancy. However, during chemotherapy, caution regarding risk of spontaneous abortion, intrauterine fetal growth retardation, teratogenicity, intrauterine fetal death, fetal immunosupression and preterm labor should be taken. Acute leukemia in pregnancy is extremely rare, so treatment and management of the pregnant mother bearing viable fetus in her 3rd trimester is not established clearly. We experienced a patient with acute lymphocytic leukemia who was first diagnosed at 27 gestational weeks and immediately started with chemotherapy. But due to preterm labor and impending fetal distress, emergency cesarean section was performed at 28 gestational weeks. We present this patient along with past experiences of acute leukemia in pregnancy.
Files in This Item:
T200500138.pdf Download
DOI
OAK-2005-02692
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kwon, Ja Young(권자영) ORCID logo https://orcid.org/0000-0003-3009-6325
Kim, Sung Hoon(김성훈) ORCID logo https://orcid.org/0000-0002-1645-7473
Kim, Young Han(김영한) ORCID logo https://orcid.org/0000-0003-0645-6028
Min, Yoo Hong(민유홍) ORCID logo https://orcid.org/0000-0001-8542-9583
Park, Yong Won(박용원)
Cheong, June-Won(정준원) ORCID logo https://orcid.org/0000-0002-1744-0921
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/147396
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