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Does long-term lactation protect premenopausal women against hypertension risk? a Korean women's cohort study

Authors
 Soon Young Lee  ;  Miyong T. Kim  ;  Sun Ha Jee  ;  Hannah Phil Yang 
Citation
 PREVENTIVE MEDICINE, Vol.41(2) : 433-438, 2005 
Journal Title
 PREVENTIVE MEDICINE 
ISSN
 0091-7435 
Issue Date
2005
MeSH
Adult ; Female ; Humans ; Hypertension/epidemiology* ; Hypertension/prevention & control ; Incidence ; Korea/epidemiology ; Lactation/physiology* ; Middle Aged ; Multivariate Analysis ; Obesity/physiopathology ; Premenopause* ; Proportional Hazards Models ; Prospective Studies ; Risk
Keywords
Hypertension ; Lactation ; Obesity ; Premenopause
Abstract
BACKGROUND: Little is known about the long-term effect of lactation on maternal cardiovascular health except for a few animal or human experimental studies. The objective of this study was to examine the effects of lactation on the incidence of hypertension in premenopausal women. METHODS: The data were derived from a cohort study with 6 years follow-up (1995-2000). The cohort was composed of 177,749 Korean premenopausal women, aged 20-59, who had medical evaluations in 1992 and 1994. During the follow-up, blood pressure was measured as part of the 1996, 1998, and 2000 periodic examinations. RESULTS: In multivariate Cox proportional hazard models, lactation decreased the risk of hypertension (risk ratio, 0.92; 95% confidence interval, 0.90-0.96). Compared with women who with no history of lactation, 1-6 months of lactation decreased the risk of hypertension (RR, 0.90; 95% CI, 0.87-0.93), as did 7-12 months (RR, 0.92; 95% CI, 0.87-0.98) or 13-18 months (RR, 0.93; 95% CI, 0.86-0.99). In particular, the coexistence of obesity and no lactation increased the risk of hypertension (P for interaction = 0.028). CONCLUSION: This finding suggests that lactation may be a protective factor against hypertension among premenopausal women.
Full Text
http://www.sciencedirect.com/science/article/pii/S0091743504005912
DOI
10.1016/j.ypmed.2004.11.025
Appears in Collections:
4. Graduate School of Public Health (보건대학원) > Graduate School of Public Health (보건대학원) > 1. Journal Papers
Yonsei Authors
Jee, Sun Ha(지선하) ORCID logo https://orcid.org/0000-0001-9519-3068
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/147336
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