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전산화 단층 촬영으로 평가한 교근에 대한 보툴리눔 A형 독소주사와 교합안정장치의 효과

Other Titles
 Effect of Botulinum Toxin type A and Occlusal Splint on Masseter Muscle Evaluated with Computed Tomographic Measurement 
 장희영  ;  강승철  ;  김성택  ;  김종열  ;  최종훈 
 Journal of Korean Academy of Oral Medicine (대한구강내과학회지), Vol.30(2) : 247-255, 2005 
Journal Title
Journal of Korean Academy of Oral Medicine(대한구강내과학회지)
Issue Date
The purpose of this study is to evaluate the effect of botulinum toxin type A on masseter muscle atrophy and the extent of masseter muscle affected from the injection site in relation to injection dose, with and without occlusal splint therapy through computed tomographic measurement.
32 volunteers were divided into four groups - group 25U (injection dose of 25 unit), group 25Us (injection dose of 25 unit with occlusal splint), group 35U (injection dose of 35 unit), group 35Us (injection dose of 35 unit with occlusal splint). Each group consisted of 8 people. 3 positions (position 1, 2, 3 - 10mm, 20mm and 40mm from the inferior border of the mandible, respectively) were selected for the evaluation of the masseter muscle change. The following results were obtained.
1. The thickness and the cross-sectional area of the masseter muscle had reduced in all groups except for the right side thickness at position 3 of group 25U and group 25Us, and the right side thickness as well as the left side cross-sectional area at position 3 of group 35Us. In group 35Us, the thickness and the cross-sectional area of the masseter muscle had reduced significantly in all positions (P < 0.05).
2. There was no significant difference in the masseter muscle change between the injection dose of 25unit and that of 35unit.
3. The groups with occlusal splint showed greater reduction of the masseter muscle thickness than the other groups (P < 0.05).
From the above results, botulinum toxin type A injection together with occlusal splint therapy in the treatment of masseter muscle hypertrophy would be clinically effective.
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Orofacial Pain and Oral Medicine (구강내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Seong Taek(김성택)
Kim, Jong Youl(김종열)
Choi, Jong Hoon(최종훈) ORCID logo https://orcid.org/0000-0003-3211-3619
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