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Health-Related Quality of Life of Kidney Transplantation Patients: Results from the KoreaN Cohort Study for Outcome in Patients With Kidney Transplantation (KNOW-KT) Study.

Authors
 H.J. Lim  ;  T.Y. Koo  ;  J. Lee  ;  K.H. Huh  ;  J.B. Park  ;  J. Cho  ;  S. Lee  ;  H. Ro  ;  S. Han  ;  B. Park  ;  S. Park  ;  W. Chung  ;  S.K. Park  ;  C. Kim  ;  S.J. Kim  ;  Y.S. Kim  ;  C. Ahn  ;  J. Yang  ;  the KNOW-KT Study Group 
Citation
 Transplantation Proceedings, Vol.48(3) : 844-847, 2016 
Journal Title
 Transplantation Proceedings 
ISSN
 0041-1345 
Issue Date
2016
MeSH
Adult ; Body Mass Index ; Cohort Studies ; Female ; Follow-Up Studies* ; Glomerular Filtration Rate ; Humans ; Kidney Transplantation* ; Male ; Middle Aged ; Quality of Life ; Republic of Korea ; Young Adult
Abstract
BACKGROUND: As patient and graft survival rates have been improving after kidney transplantation, health-related quality of life (HR-QOL) has become an important indicator of effective treatment. This study aimed to evaluate changes in HR-QOL after kidney transplantation. MATERIALS AND METHODS: The KoreaN cohort study for Outcome in patients With Kidney Transplantation (KNOW-KT) is a multicenter, observational, 9-year, cohort study. The HR-QOL of patients in the KNOW-KT study was assessed before transplantation and 2 years after transplantation using the Kidney Disease Quality of Life Short Form (KDQOL-SF) including chronic kidney disease targeted area and the Medical Outcome Study 36-item Short Form Health Survey (SF-36). Multivariate linear regression was used to identify significant factors associated with follow-up QOL scores. RESULTS: A total of 175 patients from 8 centers were analyzed. All QOL scores including the total QOL score, chronic kidney disease targeted score, and SF-36 at the 2-year follow-up were significantly increased compared to baseline values. Both physical and mental scale scores were improved after transplantation. CONCLUSION: The QOL scores for both the mental and physical scales were improved at 2 years after kidney transplantation. High glomerular filtration rate at 2 years, high baseline QOL score, and low body mass index were associated with good follow-up QOL scores. Kidney transplantation for an Asian population with end-stage renal disease can result in better QOL as well as better patient and graft survival.
Full Text
http://www.sciencedirect.com/science/article/pii/S0041134516002207
DOI
10.1016/j.transproceed.2015.12.101
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
김유선(Kim, Yu Seun) ORCID logo https://orcid.org/0000-0002-5105-1567
허규하(Huh, Kyu Ha) ORCID logo https://orcid.org/0000-0003-1364-6989
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/147096
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