Cited 3 times in
Retinal Nerve Fiber Layer Thickness is Decreased in Patients With Hematologic Malignancy.
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김지현 | - |
dc.contributor.author | 김찬윤 | - |
dc.contributor.author | 성공제 | - |
dc.contributor.author | 한승한 | - |
dc.contributor.author | 한진우 | - |
dc.contributor.author | 홍사민 | - |
dc.date.accessioned | 2017-02-27T08:07:46Z | - |
dc.date.available | 2017-02-27T08:07:46Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 1057-0829 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/147095 | - |
dc.description.abstract | PURPOSE: To investigate whether retinal nerve fiber layer (RNFL) thickness is decreased in patients with hematologic malignancy using optical coherence tomography (OCT). PATIENTS AND METHODS: This prospective, observational cross-sectional study included 65 eyes from 34 patients with hematologic malignancy and 72 healthy control eyes. OCT-measured RNFL thickness parameters (average, 4 quadrants, and 12 clock-hour thickness) and RNFL defect in red-free photo were compared between patients with hematologic malignancy and controls. RESULTS: Among average, quadrant, and clock-hour map, the only 11-o'clock RNFL in patients with hematologic malignancy was statistically thinner than in controls (P=0.021). The RNFL defect was detected in 21/65 (32.3%) patients with hematologic malignancy and in 5/72 (6.9%) controls (P<0.001). In patients with hematologic malignancy, the mean RNFL thickness was significantly lower in the severe and moderate anemia groups compared with the mild anemia group (P=0.011). In the generalized estimating equations model, the mean hemoglobin level was associated with RNFL thickness while correcting for inter-eye correlation, age, and refraction error (coefficient=3.685, P=0.006). CONCLUSIONS: The RNFL defect was frequently observed, and the RNFL was thinner in severe anemic patients with hematologic malignancy. These results suggest that chronic anemia may be a factor of RNFL loss. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.format.extent | e175~e181 | - |
dc.language | English | - |
dc.publisher | Wolters Kluwer Health, Inc. | - |
dc.relation.isPartOf | JOURNAL OF GLAUCOMA | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Anemia, Iron-Deficiency/blood | - |
dc.subject.MESH | Anemia, Iron-Deficiency/complications* | - |
dc.subject.MESH | Anemia, Iron-Deficiency/diagnosis | - |
dc.subject.MESH | Bone Marrow Transplantation | - |
dc.subject.MESH | Cross-Sectional Studies | - |
dc.subject.MESH | Erythrocyte Count | - |
dc.subject.MESH | Erythrocyte Indices | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Gonioscopy | - |
dc.subject.MESH | Hemoglobins/metabolism | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Intraocular Pressure | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Nerve Fibers/pathology* | - |
dc.subject.MESH | Optic Nerve Diseases/blood | - |
dc.subject.MESH | Optic Nerve Diseases/diagnosis | - |
dc.subject.MESH | Optic Nerve Diseases/etiology* | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Retinal Ganglion Cells/pathology* | - |
dc.subject.MESH | Tomography, Optical Coherence/methods | - |
dc.subject.MESH | Tonometry, Ocular | - |
dc.subject.MESH | Vision Disorders/physiopathology | - |
dc.subject.MESH | Visual Field Tests | - |
dc.subject.MESH | Visual Fields/physiology | - |
dc.title | Retinal Nerve Fiber Layer Thickness is Decreased in Patients With Hematologic Malignancy. | - |
dc.type | Article | - |
dc.publisher.location | United States | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Ophthalmology | - |
dc.contributor.googleauthor | Jinu Han | - |
dc.contributor.googleauthor | Ji Hyun Kim | - |
dc.contributor.googleauthor | Hanna Yoo | - |
dc.contributor.googleauthor | Sueng-Han Han | - |
dc.contributor.googleauthor | Samin Hong | - |
dc.contributor.googleauthor | Gong Je Seong | - |
dc.contributor.googleauthor | Chan Yun Kim | - |
dc.identifier.doi | 10.1097/IJG.0000000000000224 | - |
dc.contributor.localId | A00998 | - |
dc.contributor.localId | A01035 | - |
dc.contributor.localId | A01946 | - |
dc.contributor.localId | A04303 | - |
dc.contributor.localId | A04329 | - |
dc.contributor.localId | A04395 | - |
dc.relation.journalcode | J01426 | - |
dc.identifier.eissn | 1536-481X | - |
dc.identifier.pmid | 25642813 | - |
dc.identifier.url | http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00061198-201603000-00026&LSLINK=80&D=ovft | - |
dc.subject.keyword | retinal nerve fiber layer | - |
dc.subject.keyword | anemia | - |
dc.subject.keyword | nonarteritic ischemic optic neuropathy | - |
dc.contributor.alternativeName | Kim, Ji Hyun | - |
dc.contributor.alternativeName | Kim, Chan Yun | - |
dc.contributor.alternativeName | Seong, Gong Je | - |
dc.contributor.alternativeName | Han, Seung Han | - |
dc.contributor.alternativeName | Han, Jin U | - |
dc.contributor.alternativeName | Hong, Sa Min | - |
dc.contributor.affiliatedAuthor | Kim, Ji Hyun | - |
dc.contributor.affiliatedAuthor | Kim, Chan Yun | - |
dc.contributor.affiliatedAuthor | Seong, Gong Je | - |
dc.contributor.affiliatedAuthor | Han, Seung Han | - |
dc.contributor.affiliatedAuthor | Han, Jin U | - |
dc.contributor.affiliatedAuthor | Hong, Sa Min | - |
dc.citation.volume | 25 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 175 | - |
dc.citation.endPage | 181 | - |
dc.identifier.bibliographicCitation | JOURNAL OF GLAUCOMA, Vol.25(3) : 175-181, 2016 | - |
dc.date.modified | 2017-02-24 | - |
dc.identifier.rimsid | 47127 | - |
dc.type.rims | ART | - |
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