Cited 6 times in
Early Marker of Myocardial Deformation in Children with Duchenne Muscular Dystrophy Assessed Using Echocardiographic Myocardial Strain Analysis.
DC Field | Value | Language |
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dc.contributor.author | 강성웅 | - |
dc.contributor.author | 은영민 | - |
dc.contributor.author | 정조원 | - |
dc.contributor.author | 조원하 | - |
dc.contributor.author | 최재영 | - |
dc.date.accessioned | 2017-02-27T08:02:29Z | - |
dc.date.available | 2017-02-27T08:02:29Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/147065 | - |
dc.description.abstract | PURPOSE: As cardiomyopathy is more prevalent and currently the leading cause of death in Duchenne muscular dystrophy (DMD), early detection of myocardial involvement is important. The purpose of this study was to analyze myocardial strain in DMD children, for the possibility of early detection of myocardial dysfunction. MATERIALS AND METHODS: We reviewed medical records of DMD patients who were >10 years of age (15.6±1.6 years, 12.5-18 years), from March 2013 to June 2014. Data of 24 DMD children who underwent echocardiography with three-layer specific myocardial strain were compared with 24 controls (age: 9.3±4.0 years, 5.5-17 years). RESULTS: Epicardial longitudinal strain was lower in DMD (DMD: -9.3±3.8%; control: -12.3±4.3%; p=0.012). Radial strain (DMD: 24.1±11.1%; control: 37.3±25.9%; p=0.027) and strain rate (SR) (DMD: 1.68±0.91; control: 2.42±0.84; p=0.006) on parasternal short axis view were lower in DMD. Circumferential strains in the endocardium (DMD: -17.5±4.7%; control: -24.2±5.3%; p<0.001), myocardium (DMD: -12.7±3.8%; control: -18.0±4.0%; p<0.001), and epicardium (DMD: -8.4±4.0%; control: -12.2±5.0%; p=0.006) were significantly decreased in DMD. Circumferential SRs were lower in the endocardial (DMD: -1.46±0.38; control: -1.78±0.27; p=0.002) and myocardial layers (DMD: 1.02±0.27; control: -1.28±0.22; p=0.001). CONCLUSION: In DMD patients, deteriorations in myocardial circumferential strain might be an indicator for predicting cardiomyopathy. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 900~904 | - |
dc.language | English | - |
dc.publisher | Yonsei University | - |
dc.relation.isPartOf | YONSEI MEDICAL JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Cardiomyopathies/diagnostic imaging* | - |
dc.subject.MESH | Cardiomyopathies/etiology* | - |
dc.subject.MESH | Case-Control Studies | - |
dc.subject.MESH | Child | - |
dc.subject.MESH | Child, Preschool | - |
dc.subject.MESH | Early Diagnosis | - |
dc.subject.MESH | Echocardiography* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Muscular Dystrophy, Duchenne/complications* | - |
dc.subject.MESH | Muscular Dystrophy, Duchenne/diagnostic imaging* | - |
dc.subject.MESH | Predictive Value of Tests | - |
dc.title | Early Marker of Myocardial Deformation in Children with Duchenne Muscular Dystrophy Assessed Using Echocardiographic Myocardial Strain Analysis. | - |
dc.type | Article | - |
dc.publisher.location | Korea (South) | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Rehabilitation Medicine | - |
dc.contributor.googleauthor | Won Ha Jo | - |
dc.contributor.googleauthor | Lucy Youngmin Eun | - |
dc.contributor.googleauthor | Jo Won Jung | - |
dc.contributor.googleauthor | Jae Young Choi | - |
dc.contributor.googleauthor | Seung Woong Gang | - |
dc.identifier.doi | 10.3349/ymj.2016.57.4.900 | - |
dc.contributor.localId | A00041 | - |
dc.contributor.localId | A02634 | - |
dc.contributor.localId | A03720 | - |
dc.contributor.localId | A04681 | - |
dc.contributor.localId | A04174 | - |
dc.relation.journalcode | J02813 | - |
dc.identifier.eissn | 1976-2437 | - |
dc.identifier.pmid | 27189283 | - |
dc.subject.keyword | Duchenne muscular dystrophy | - |
dc.subject.keyword | cardiomyopathies | - |
dc.subject.keyword | children | - |
dc.subject.keyword | myocardial strain | - |
dc.contributor.alternativeName | Kang, Seong Woong | - |
dc.contributor.alternativeName | Eun, Young Min | - |
dc.contributor.alternativeName | Jung, Jo Won | - |
dc.contributor.alternativeName | Jo, Won Ha | - |
dc.contributor.alternativeName | Choi, Jae Young | - |
dc.contributor.affiliatedAuthor | Kang, Seong Woong | - |
dc.contributor.affiliatedAuthor | Eun, Young Min | - |
dc.contributor.affiliatedAuthor | Jung, Jo Won | - |
dc.contributor.affiliatedAuthor | Jo, Won Ha | - |
dc.contributor.affiliatedAuthor | Choi, Jae Young | - |
dc.citation.volume | 57 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 900 | - |
dc.citation.endPage | 904 | - |
dc.identifier.bibliographicCitation | YONSEI MEDICAL JOURNAL, Vol.57(4) : 900-904, 2016 | - |
dc.date.modified | 2017-02-24 | - |
dc.identifier.rimsid | 47097 | - |
dc.type.rims | ART | - |
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