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Left Atrial Appendage Occlusion in Non-Valvular Atrial Fibrillation in a Korean Multi-Center Registry.

Authors
 Jung-Sun Kim  ;  Hancheol Lee  ;  Yongsung Suh  ;  Hui-Nam Pak  ;  Geu-Ru Hong  ;  Chi Young Shim  ;  Cheol-Woong Yu  ;  Hyun-Jong Lee  ;  Woong-Chol Kang  ;  Eun-Seok Shin  ;  Rak-Kyeong Choi  ;  Saibal Kar  ;  Jai-Wun Park  ;  Do-Sun Lim  ;  Yangsoo Jang 
Citation
 CIRCULATION JOURNAL, Vol.80(5) : 1123-1130, 2016 
Journal Title
 CIRCULATION JOURNAL 
ISSN
 1346-9843 
Issue Date
2016
MeSH
Aged ; Atrial Appendage/surgery* ; Atrial Fibrillation/complications* ; Atrial Fibrillation/surgery ; Equipment and Supplies/standards* ; Female ; Humans ; Male ; Middle Aged ; Registries ; Republic of Korea ; Stroke/prevention & control ; Treatment Outcome
Keywords
Atrial fibrillation ; Left atrial appendage occlusion ; Stroke
Abstract
BACKGROUND: The aim of this study was to evaluate clinical outcome after left atrial appendage (LAA) occlusion in real clinical practice and compare between Amplatzer cardiac plug (ACP) and Watchman. METHODS AND RESULTS: From October 2010 to February 2015, 96 successful LAA occlusion procedures were performed using either ACP (n=50) or Watchman device (n=46) in non-valvular atrial fibrillation (AF) patients (59 male; age, 65.1±9.4 years; CHADS2, 2.5±1.2; CHA2DS2-VASC, 3.9±1.6; HAS-BLED, 2.7±1.3). The procedure success rate was 96.8%. There were serious complications in 4 patients (4.1%; 2 cardiac tamponade, 1 device embolization, and 1 major bleed). The anticoagulation cessation rate after 6 weeks was 92.7%. During mean 21.9-month follow-up, the incidence of death, stroke, systemic embolization and major bleeding was 5.2%, 4.2%, 0% and 1.0%, respectively. On transesophageal echocardiography of 93 patients within 6 months after the procedure, 24 residual leaks were observed (25.8%; 2 mild, 18 moderate, and 4 major). Clinical outcome was similar for the 2 devices, but peridevice leakage was more frequent with the Watchman than the ACP. CONCLUSIONS: LAA occlusion was feasible in non-valvular AF patients with high risk of stroke and hemorrhage. The ACP and Watchman devices were similar in terms of procedural and clinical outcomes. (Circ J 2016; 80: 1123-1130).
Files in This Item:
T201601960.pdf Download
DOI
10.1253/circj.CJ-15-1134
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jung Sun(김중선) ORCID logo https://orcid.org/0000-0003-2263-3274
Pak, Hui Nam(박희남) ORCID logo https://orcid.org/0000-0002-3256-3620
Shim, Chi Young(심지영) ORCID logo https://orcid.org/0000-0002-6136-0136
Jang, Yang Soo(장양수) ORCID logo https://orcid.org/0000-0002-2169-3112
Hong, Geu Ru(홍그루) ORCID logo https://orcid.org/0000-0003-4981-3304
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/147030
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