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Impact of Braun anastomosis on reducing delayed gastric emptying following pancreaticoduodenectomy: a prospective, randomized controlled trial.

Authors
 Ho Kyoung Hwang  ;  Sung Hwan Lee  ;  Dai Hoon Han  ;  Sung Hoon Choi  ;  Chang Moo Kang  ;  Woo Jung Lee 
Citation
 Journal of Hepato-Biliary-Pancreatic Sciences, Vol.23(6) : 364-372, 2016 
Journal Title
 Journal of Hepato-Biliary-Pancreatic Sciences 
ISSN
 1868-6974 
Issue Date
2016
MeSH
Adult ; Aged ; Anastomosis, Surgical/methods ; Female ; Follow-Up Studies ; Gastric Emptying/physiology ; Gastroparesis/prevention & control* ; Humans ; Male ; Middle Aged ; Pancreatic Neoplasms/diagnostic imaging ; Pancreatic Neoplasms/pathology ; Pancreatic Neoplasms/surgery* ; Pancreaticoduodenectomy/adverse effects* ; Pancreaticoduodenectomy/methods ; Postoperative Complications/prevention & control* ; Prospective Studies ; Risk Assessment ; Time Factors ; Treatment Outcome
Keywords
Braun anastomosis ; Delayed gastric emptying ; Pancreaticoduodenectomy
Abstract
BACKGROUND: The present study investigates the clinical impact of Braun anastomosis on delayed gastric emptying (DGE) after pylorus-preserving pancreaticoduodenectomy (PPPD). METHODS: From February 2013 to June 2014, 60 patients were recruited for this randomized controlled trial. The incidence of DGE and its risk factors were analyzed according to whether or not Braun anastomosis was used after PPPD. RESULTS: Thirty patients were respectively enrolled in No-Braun group and Braun group. A comparative analysis between the two groups showed no differences in sex, diagnosis, operation time, hospital stay, or postoperative complications, including pancreatic fistula. Overall DGE developed in eight patients (26.7%) in the Braun group and in 14 patients (46.7%) in the No-Braun group (P = 0.108). However, clinically relevant DGE (grades B and C) was marginally more frequent in the No-Braun group (23.3% vs. 3.3%, P = 0.052). In a multivariable analysis, No-Braun anastomosis was an independent risk factor for developing clinically relevant DGE (odds ratio = 16.489; 95% confidence interval: 1.287-211.195; P = 0.031). CONCLUSION: The overall DGE occurrence was not different between the two groups. However, No-Braun anastomosis was an independent risk factor for developing clinically relevant DGE.
Full Text
http://onlinelibrary.wiley.com/doi/10.1002/jhbp.349/abstract
DOI
10.1002/jhbp.349
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
강창무(Kang, Chang Moo) ORCID logo https://orcid.org/0000-0002-5382-4658
이성환(Lee, Sung Hwan)
이우정(Lee, Woo Jung) ORCID logo https://orcid.org/0000-0001-9273-261X
한대훈(Han, Dai Hoon) ORCID logo https://orcid.org/0000-0003-2787-7876
황호경(Hwang, Ho Kyoung) ORCID logo https://orcid.org/0000-0003-4064-7776
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/146993
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