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Pathologic Evaluation of Breast Cancer after Neoadjuvant Therapy

Authors
 Cheol Keun Park  ;  Woo-Hee Jung  ;  Ja Seung Koo 
Citation
 JOURNAL OF PATHOLOGY AND TRANSLATIONAL MEDICINE, Vol.50(3) : 173-180, 2016 
Journal Title
 JOURNAL OF PATHOLOGY AND TRANSLATIONAL MEDICINE 
ISSN
 2383-7837 
Issue Date
2016
Keywords
Breast neoplasms ; Neoadjuvant therapy ; Pathologic response evaluation
Abstract
Breast cancer, one of the most common cancers in women, has various treatment modalities. Neoadjuvant therapy (NAT) has been used in many clinical trials because it is easy to evaluate the treatment response to therapeutic agents in a short time period; consequently, NAT is currently a standard treatment modality for large-sized and locally advanced breast cancers, and its use in early-stage breast cancer is becoming more common. Thus, chances to encounter breast tissue from patients treated with NAT is increasing. However, systems for handling and evaluating such specimens have not been established. Several evaluation systems emphasize a multidisciplinary approach to increase the accuracy of breast cancer assessment. Thus, detailed and systematic evaluation of clinical, radiologic, and pathologic findings is important. In this review, we compare the major problems of each evaluation system and discuss important points for handling and evaluating NAT-treated breast specimens.
Files in This Item:
T201601585.pdf Download
DOI
10.4132/jptm.2016.02.02
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
Yonsei Authors
Koo, Ja Seung(구자승) ORCID logo https://orcid.org/0000-0003-4546-4709
Jung, Woo Hee(정우희)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/146885
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