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Botulinum Toxin Type A Injection for Spastic Equinovarus Foot in Children with Spastic Cerebral Palsy: Effects on Gait and Foot Pressure Distribution

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dc.contributor.author나동욱-
dc.contributor.author박은숙-
dc.contributor.author최자영-
dc.date.accessioned2017-02-24T07:54:48Z-
dc.date.available2017-02-24T07:54:48Z-
dc.date.issued2016-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/146556-
dc.description.abstractPURPOSE: To investigate the effect of intramuscular Botulinum toxin type A (BoNT-A) injection on gait and dynamic foot pressure distribution in children with spastic cerebral palsy (CP) with dynamic equinovarus foot. MATERIALS AND METHODS: Twenty-five legs of 25 children with CP were investigated in this study. BoNT-A was injected into the gastrocnemius (GCM) and tibialis posterior (TP) muscles under the guidance of ultrasonography. The effects of the toxin were clinically assessed using the modified Ashworth scale (MAS) and modified Tardieu scale (MTS), and a computerized gait analysis and dynamic foot pressure measurements using the F-scan system were also performed before injection and at 1 and 4 months after injection. RESULTS: Spasticity of the ankle plantar-flexor in both the MAS and MTS was significantly reduced at both 1 and 4 months after injection. On dynamic foot pressure measurements, the center of pressure index and coronal index, which represent the asymmetrical weight-bearing of the medial and lateral columns of the foot, significantly improved at both 1 and 4 months after injection. The dynamic foot pressure index, total contact area, contact length and hind foot contact width all increased at 1 month after injection, suggesting better heel contact. Ankle kinematic data were significantly improved at both 1 and 4 months after injection, and ankle power generation was significantly increased at 4 months after injection compared to baseline data. CONCLUSION: Using a computerized gait analysis and foot scan, this study revealed significant benefits of BoNT-A injection into the GCM and TP muscles for dynamic equinovarus foot in children with spastic CP.-
dc.description.statementOfResponsibilityopen-
dc.format.extent496~504-
dc.languageEnglish-
dc.publisherYonsei University-
dc.relation.isPartOfYONSEI MEDICAL JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdolescent-
dc.subject.MESHAnkle Joint-
dc.subject.MESHBotulinum Toxins, Type A/administration & dosage-
dc.subject.MESHBotulinum Toxins, Type A/pharmacology*-
dc.subject.MESHCerebral Palsy/complications*-
dc.subject.MESHCerebral Palsy/drug therapy-
dc.subject.MESHChild-
dc.subject.MESHChild, Preschool-
dc.subject.MESHClubfoot/drug therapy*-
dc.subject.MESHClubfoot/etiology*-
dc.subject.MESHClubfoot/physiopathology-
dc.subject.MESHFemale-
dc.subject.MESHFoot-
dc.subject.MESHGait/drug effects*-
dc.subject.MESHGait/physiology-
dc.subject.MESHHumans-
dc.subject.MESHInjections, Intramuscular-
dc.subject.MESHMale-
dc.subject.MESHMuscle Spasticity/drug therapy-
dc.subject.MESHMuscle, Skeletal/diagnostic imaging-
dc.subject.MESHNeuromuscular Agents/administration & dosage-
dc.subject.MESHNeuromuscular Agents/pharmacology*-
dc.subject.MESHPressure-
dc.subject.MESHProspective Studies-
dc.subject.MESHTreatment Outcome-
dc.subject.MESHWeight-Bearing-
dc.titleBotulinum Toxin Type A Injection for Spastic Equinovarus Foot in Children with Spastic Cerebral Palsy: Effects on Gait and Foot Pressure Distribution-
dc.typeArticle-
dc.publisher.locationKorea (South)-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Rehabilitation Medicine-
dc.contributor.googleauthorJa Young Choi-
dc.contributor.googleauthorSoojin Jung-
dc.contributor.googleauthorDong-wook Rha-
dc.contributor.googleauthorEun Sook Park-
dc.identifier.doi10.3349/ymj.2016.57.2.496-
dc.contributor.localIdA01230-
dc.contributor.localIdA01611-
dc.contributor.localIdA04170-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid26847306-
dc.subject.keywordBotulinum toxin type A-
dc.subject.keywordcerebral palsy-
dc.subject.keywordequinovarus deformity-
dc.contributor.alternativeNameRha, Dong Wook-
dc.contributor.alternativeNamePark, Eun Sook-
dc.contributor.alternativeNameChoi, Ja Young-
dc.contributor.affiliatedAuthorRha, Dong Wook-
dc.contributor.affiliatedAuthorPark, Eun Sook-
dc.contributor.affiliatedAuthorChoi, Ja Young-
dc.citation.volume57-
dc.citation.number2-
dc.citation.startPage496-
dc.citation.endPage504-
dc.identifier.bibliographicCitationYONSEI MEDICAL JOURNAL, Vol.57(2) : 496-504, 2016-
dc.date.modified2017-02-24-
dc.identifier.rimsid45187-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학교실) > 1. Journal Papers

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