0 560

Cited 47 times in

Assessments of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in Korean patients with psoriasis vulgaris and psoriatic arthritis

 Dae Suk KIM  ;  Dongyun SHIN  ;  Min Seok LEE  ;  Hee Ju KIM  ;  Do Young KIM  ;  Soo Min KIM  ;  Min-Geol LEE 
 JOURNAL OF DERMATOLOGY, Vol.42(3) : 305-310, 2016 
Journal Title
Issue Date
Arthritis, Psoriatic/blood* ; Arthritis, Psoriatic/pathology ; Asian Continental Ancestry Group ; Case-Control Studies ; Cross-Sectional Studies ; Humans ; Leukocyte Count ; Neutrophils ; Platelet Count ; Psoriasis/blood* ; Psoriasis/pathology ; Retrospective Studies
inflammation ; neutrophil to lymphocyte ratio ; platelet to lymphocyte ratio ; psoriasis vulgaris ; psoriatic arthritis
The objective of this retrospective study is to assess neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) as inflammatory markers in patients with psoriasis and psoriatic arthritis (PsA). A hundred and eleven psoriasis patients and 25 PsA patients were compared with 94 healthy controls. Demographic, clinical and laboratory information were collected and analyzed. NLR and PLR were calculated. White blood cell (WBC), neutrophils, eosinophils and NLR were increased in psoriasis patients compared with controls. WBC, neutrophils, NLR, monocytes, platelets and PLR were increased in PsA patients compared with both controls and psoriasis patients. Erythrocyte sedimentation rate (ESR) and C-reactive protein were significantly higher in PsA patients compared with psoriasis patients. Among psoriasis patients, Psoriasis Area and Severity Index (PASI) score correlated positively with platelets, NLR and PLR. These parameters were all significantly higher in moderate to severe psoriasis patients (PASI ≥ 10) compared with mild patients (PASI < 10). Elevated platelets, NLR and PLR were significantly associated with the increased PASI scores in multivariate analysis. NLR, PLR and ESR were statistically significant predictors for the presence of PsA in psoriasis patients. NLR was the strongest predictor (odds ratio = 3.351, P = 0.005). In conclusion, elevated NLR and PLR were significantly associated with psoriasis and PsA. Both NLR and PLR were strong predictors for the presence of PsA among psoriasis patients.
Full Text
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Dae Suk(김대석)
Kim, Do Young(김도영) ORCID logo https://orcid.org/0000-0002-0194-9854
Lee, Min Geol(이민걸) ORCID logo https://orcid.org/0000-0001-7040-5335
Lee, Min Seok(이민석)
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.