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Treponema lecithinolyticum 주외막단백질 (MspTL)의 역할 규명
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 유윤정 | - |
dc.date.accessioned | 2016-05-16T11:29:08Z | - |
dc.date.available | 2016-05-16T11:29:08Z | - |
dc.date.issued | 2002 | - |
dc.identifier.issn | 1225-2344 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/144654 | - |
dc.description.abstract | Treponema lecithinolyticum is known to be associated with rapidly progressive periodontitis. The full-length gene encoding the major surface protein MspTL of this organism was cloned and expressed by using the expression vector pQE30. Recombinant MspTL(rMspTL) protein was purified and functionally characterized. MspTL was one of several T. lecithinolyticum surface proteins that bound to cultured human gingival fibroblasts (HGFs). As well, it strongly induced IL-6 production by HGFs. These observations suggest that MspTL contributes to pathogenesis of periodontitis by adhesion to host cells and by induction of the proinflammatory cytokine IL-6. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 47~54 | - |
dc.relation.isPartOf | Journal of Bacteriology and Virology | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Treponema lecithinolyticum 주외막단백질 (MspTL)의 역할 규명 | - |
dc.title.alternative | Functional Characterization of the Major Outer Membrane Protein (MspTL) of Treponema lecithinolyticum | - |
dc.type | Article | - |
dc.contributor.college | College of Dentistry (치과대학) | - |
dc.contributor.department | Dept. of Oral Biology (구강생물학) | - |
dc.contributor.googleauthor | Chong Kwan Kim | - |
dc.contributor.googleauthor | Yun Jung Yoo | - |
dc.contributor.googleauthor | Young Ho Kim | - |
dc.contributor.googleauthor | Bong Kyu Choi | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02490 | - |
dc.relation.journalcode | J01255 | - |
dc.subject.keyword | Periodontitis | - |
dc.subject.keyword | Treponema lecithinolyticum | - |
dc.subject.keyword | Major surface protein | - |
dc.contributor.alternativeName | Yoo, Yun Jung | - |
dc.contributor.affiliatedAuthor | Yoo, Yun Jung | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 32 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 47 | - |
dc.citation.endPage | 54 | - |
dc.identifier.bibliographicCitation | Journal of Bacteriology and Virology, Vol.32(1) : 47-54, 2002 | - |
dc.identifier.rimsid | 51339 | - |
dc.type.rims | ART | - |
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