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Ca2+ Signaling Proteins and Mammalian Sec6/8 Complex
DC Field | Value | Language |
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dc.contributor.author | 신동민 | - |
dc.contributor.author | 이승일 | - |
dc.date.accessioned | 2016-05-16T11:26:40Z | - |
dc.date.available | 2016-05-16T11:26:40Z | - |
dc.date.issued | 2002 | - |
dc.identifier.issn | 1226-7155 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/144564 | - |
dc.description.abstract | Polarized expression of signaling complexes requires mechanisms for delivery, assembly and retention of the proteins in the microdomains. Little or no information is available as to the nature of these mechanisms in non-excitable cells. It is possible that the vesicles/protein delivery system known as the exocyst or Sec6/8 complex participate in targeting the Ca2+ signaling complex to the microdomain. The data suggested by our work demonstrate that the Sec6/8 complex mediated delivery of pre-assembled Ca2+ signaling complexes to the apical pole region most proximal to the tight junctions. A novel function of the Sec6/8 complex is that the Sec6/8 complex has multiple roles in secretory cells including governing the polarized expression of Ca2+ signaling complexes and regulation of their activity. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 91~94 | - |
dc.relation.isPartOf | International Journal of Oral Biology | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Ca2+ Signaling Proteins and Mammalian Sec6/8 Complex | - |
dc.type | Article | - |
dc.contributor.college | College of Dentistry (치과대학) | - |
dc.contributor.department | Dept. of Oral Biology (구강생물학) | - |
dc.contributor.googleauthor | Dong Min Shin | - |
dc.contributor.googleauthor | Syng Ill Lee | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02091 | - |
dc.contributor.localId | A02924 | - |
dc.relation.journalcode | J01144 | - |
dc.subject.keyword | Sec6/8 Complex | - |
dc.subject.keyword | Ca2+Signaling Proteins | - |
dc.subject.keyword | Polarity | - |
dc.subject.keyword | exocrine cells | - |
dc.contributor.alternativeName | Shin, Dong Min | - |
dc.contributor.alternativeName | Lee, Syng Ill | - |
dc.contributor.affiliatedAuthor | Shin, Dong Min | - |
dc.contributor.affiliatedAuthor | Lee, Syng Ill | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 27 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 91 | - |
dc.citation.endPage | 94 | - |
dc.identifier.bibliographicCitation | International Journal of Oral Biology, Vol.27(3) : 91-94, 2002 | - |
dc.identifier.rimsid | 51253 | - |
dc.type.rims | ART | - |
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