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The Application of Laser Doppler Flowmetry for Allergic Rhinitis and Rhinitis Medicamentosa

 Jeung Gweon Lee  ;  Joo Heon Yoon  ;  , Hyun Jun Kim  ;  In Suk Moon  ;  Jae Yol Lim  ;  Jong Bum Yoo 
 Journal of Rhinology, Vol.9(1) : 30-34, 2002 
Journal Title
 Journal of Rhinology 
Issue Date
Laser Doppler flowmetry ; Nasal blood flow·Mucosal color ; Rhinitis medicamentosa ; Allergic rhinitis
BACKGROUND AND OBJECTIVES: Allergic rhinitis (AR) and rhinitis medicamentosa (RM) have different mucosal color and pathophysiology. To investigate whether the mucosal color and nasal blood flow are different between the diseases in spite of same symptoms, we designed this study. MATERIALS AND METHODS: 20 patients with allergic rhinitis and 21 patients with rhinitis medicamentosa were compared with 20 normal volunteers using mucosal color grading and Laser Doppler flowmetry. The Laser Doppler flowmetry was performed with a Periflux 4001 (Perimed, Jrtlla, Sweden) and perfusion unit (PU), velocity unit (VU), and concentration Unit (CU) were measured. The Laser Doppler flowmetry data in AR and RM were compared with those of the normal subjects, and between AR and RM. RESULTS: The perfusion score of AR and RM were lower than the control (p<0.05) and it was statistically significant that the mucosal color of AR were pale and of RM were reddish, comparing to the control group (p<0.05). CONCLUSION: The nasal blood flow was decreased with AR and RM compared to control but the mucosal color of AR and RM were different because of the difference of pathophysiology of diseases. When diagnosing RM, observation of mucosal color and measurement of nasal blood flow will be helpful besides the history of long-term use of nasal decongestant.
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1. College of Medicine (의과대학) > Dept. of Otorhinolaryngology (이비인후과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Jeung Gweon(이정권)
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