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C-반응성단백과 심혈관질환 위험인자와의 관계
DC Field | Value | Language |
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dc.contributor.author | 심재용 | - |
dc.date.accessioned | 2016-05-16T11:20:09Z | - |
dc.date.available | 2016-05-16T11:20:09Z | - |
dc.date.issued | 2002 | - |
dc.identifier.issn | 2005-6443 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/144323 | - |
dc.description.abstract | Background: C-reactive protein is an acute phase reactant, which can be increased by either (both) infectious or (and) non-infectious and non-specific reaction of cells and tissue metabolism. Also C-reactive protein is known to have a relationship between changes, in lipid and glucose metabolism. In recent studies, the possibility of being a prognostic factor of cardiovascular risk factors and serum C-reactive protein concentration within conventional reference ranges in otherwise normal people has also received little attention. Therfore, in this study, we tried to look for the relationship between C-reactive protein and cardiovascular risk factors of a healthy adult. Methods: We analyzed the results of the surveys and general chemistries given to 3,548 healthy men and women who have visited the health promotion center in certain university hospital. We assayed the C-reactive protein by means of rate nephelometry. We omitted the case of 123 people who went over 1㎎/㎗. We compared C-reactive protein of normal and abnormal range of each risk factor and went through the multiple regression analysis for the factors with significant differences. Results: When C-reactive protein concentration of normal and abnormal range of cardiovascular risk factors were compared by t-test, there were differences according to age (p<0.001), sex (p<0.001), body mass index (p<0.001), WBC (p<0.001), wystolic blood pressure (p<0.001), diastolic pressure (p<0.001), total cholesterol (p<0.01), HDL-cholesterol (p<0.05) and smoking (p<0.01). We could not find any significant difference of triglycerides. After going through multiple regression analysis for the risk factors, which showed a significant difference by t-test, we found out that the C-reactive protein increased as cholesterol (p<0.01), body mass index (p<0.01) and WBC (p<0.001) increased. As for HDL-cholesterol (p<0.001), the C-reactive protein increased as it decreased. Age, sex, smoking history, systolic blood pressure, and diastolic blood pressure did not show significant relationship we were looking for. Conclusion: c-reactive protein was not related to age, smoking history, blood pressure, and triglycerides among cardiovascular risk factors, but was related to body mass index, cholesterol, HDL-cholesterol and WBC. This relationship indicated that even if the C-reactive protein was in normal range a person with C-reactive protein should be aware of the risk involved for cardiovascular diseases. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | Korean | - |
dc.publisher | 대한가정의학회 | - |
dc.relation.isPartOf | Journal of the Korean Academy of Family Medicine (가정의학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | C-반응성단백과 심혈관질환 위험인자와의 관계 | - |
dc.title.alternative | The relationship between C-reactive protein and cardiovascular risk factors | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Family Medicine (가정의학) | - |
dc.contributor.googleauthor | 손중천 | - |
dc.contributor.googleauthor | 한지혜 | - |
dc.contributor.googleauthor | 김지선 | - |
dc.contributor.googleauthor | 심재용 | - |
dc.contributor.googleauthor | 이혜리 | - |
dc.contributor.googleauthor | 오재준 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02207 | - |
dc.relation.journalcode | J03700 | - |
dc.identifier.eissn | 2092-6715 | - |
dc.subject.keyword | C-reactive protein | - |
dc.subject.keyword | cardiovascular diseases | - |
dc.subject.keyword | risk factors | - |
dc.contributor.alternativeName | Shim, Jae Yong | - |
dc.contributor.affiliatedAuthor | Shim, Jae Yong | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 23 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 365 | - |
dc.citation.endPage | 373 | - |
dc.identifier.bibliographicCitation | Journal of the Korean Academy of Family Medicine (가정의학회지), Vol.23(3) : 365-373, 2002 | - |
dc.identifier.rimsid | 57198 | - |
dc.type.rims | ART | - |
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