Cited 45 times in
Treatment of advanced gastric cancer by palliative gastrectomy, cytoreductive therapy and postoperative intraperitoneal chemotherapy.
DC Field | Value | Language |
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dc.contributor.author | 노성훈 | - |
dc.contributor.author | 라선영 | - |
dc.contributor.author | 정현철 | - |
dc.contributor.author | 정희철 | - |
dc.date.accessioned | 2016-05-16T11:17:40Z | - |
dc.date.available | 2016-05-16T11:17:40Z | - |
dc.date.issued | 2002 | - |
dc.identifier.issn | 0007-1323 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/144228 | - |
dc.description.abstract | Background: The treatment options for the 10–20 per cent of patients with gastric cancer who present with peritoneal dissemination are extremely limited and no standard approach exists. Methods: The feasibility of using intraperitoneal chemotherapy to treat gastric cancer with intra-abdominal gross residual lesions after palliative gastrectomy with maximal cytoreduction was investigated. Early postoperative intraperitoneal chemotherapy started on the day of operation with 5-fluorouracil 500 mg/m2 and cisplatin 40 mg/m2 (days 1–3) over a 4-week interval. Results: Of the 53 patients enrolled between July 1994 and December 1998, 49 were eligible. The progression-free survival (PFS) was 7 months and the overall survival was 12 months. In multivariate analysis, performance status was the only significant defining factor for PFS (P = 0·009). The predominant toxicity was neutropenia and nausea/vomiting. The relative dose intensity of 5-fluorouracil and cisplatin was 89 and 63 per cent respectively. Conclusion: Performance status emerged as a major determining factor for prognosis and patient selection for early postoperative intraperitoneal chemotherapy in patients with advanced gastric cancer after maximally cytoreductive surgery. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 460~466 | - |
dc.relation.isPartOf | BRITISH JOURNAL OF SURGERY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adenocarcinoma/drugtherapy* | - |
dc.subject.MESH | Adenocarcinoma/surgery* | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Antineoplastic CombinedChemotherapyProtocols/adverse effects | - |
dc.subject.MESH | Antineoplastic CombinedChemotherapyProtocols/therapeutic use* | - |
dc.subject.MESH | Child | - |
dc.subject.MESH | Child, Preschool | - |
dc.subject.MESH | Cisplatin/administration & dosage | - |
dc.subject.MESH | Cisplatin/adverse effects | - |
dc.subject.MESH | Combined ModalityTherapy/methods | - |
dc.subject.MESH | Disease-Free Survival | - |
dc.subject.MESH | Feasibility Studies | - |
dc.subject.MESH | Fluorouracil/administration & dosage | - |
dc.subject.MESH | Fluorouracil/adverse effects | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Infant | - |
dc.subject.MESH | Infant, Newborn | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | NeoplasmStaging/methods | - |
dc.subject.MESH | PalliativeCare/methods* | - |
dc.subject.MESH | Stomach Neoplasms/drugtherapy* | - |
dc.subject.MESH | Stomach Neoplasms/surgery* | - |
dc.title | Treatment of advanced gastric cancer by palliative gastrectomy, cytoreductive therapy and postoperative intraperitoneal chemotherapy. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학) | - |
dc.contributor.googleauthor | H. C. Jeung | - |
dc.contributor.googleauthor | S. Y. Rha | - |
dc.contributor.googleauthor | W. I. Jang | - |
dc.contributor.googleauthor | S. H. Noh | - |
dc.contributor.googleauthor | H. C. Chung | - |
dc.identifier.doi | 10.1046/j.0007-1323.2001.02048.x | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01281 | - |
dc.contributor.localId | A03773 | - |
dc.contributor.localId | A01316 | - |
dc.contributor.localId | A03794 | - |
dc.relation.journalcode | J00418 | - |
dc.identifier.eissn | 1365-2168 | - |
dc.identifier.pmid | 11952588 | - |
dc.identifier.url | http://onlinelibrary.wiley.com/doi/10.1046/j.0007-1323.2001.02048.x/abstract | - |
dc.contributor.alternativeName | Noh, Sung Hoon | - |
dc.contributor.alternativeName | Rha, Sun Young | - |
dc.contributor.alternativeName | Chung, Hyun Cheol | - |
dc.contributor.alternativeName | Jeung, Hei Cheul | - |
dc.contributor.affiliatedAuthor | Noh, Sung Hoon | - |
dc.contributor.affiliatedAuthor | Chung, Hyun Cheol | - |
dc.contributor.affiliatedAuthor | Rha, Sun Young | - |
dc.contributor.affiliatedAuthor | Jeung, Hei Cheul | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 89 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 460 | - |
dc.citation.endPage | 466 | - |
dc.identifier.bibliographicCitation | BRITISH JOURNAL OF SURGERY, Vol.89(4) : 460-466, 2002 | - |
dc.identifier.rimsid | 56700 | - |
dc.type.rims | ART | - |
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