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Cited 41 times in

Treatment of advanced gastric cancer by palliative gastrectomy, cytoreductive therapy and postoperative intraperitoneal chemotherapy.

DC FieldValueLanguage
dc.contributor.author노성훈-
dc.contributor.author라선영-
dc.contributor.author정현철-
dc.contributor.author정희철-
dc.date.accessioned2016-05-16T11:17:40Z-
dc.date.available2016-05-16T11:17:40Z-
dc.date.issued2002-
dc.identifier.issn0007-1323-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/144228-
dc.description.abstractBackground: The treatment options for the 10–20 per cent of patients with gastric cancer who present with peritoneal dissemination are extremely limited and no standard approach exists. Methods: The feasibility of using intraperitoneal chemotherapy to treat gastric cancer with intra-abdominal gross residual lesions after palliative gastrectomy with maximal cytoreduction was investigated. Early postoperative intraperitoneal chemotherapy started on the day of operation with 5-fluorouracil 500 mg/m2 and cisplatin 40 mg/m2 (days 1–3) over a 4-week interval. Results: Of the 53 patients enrolled between July 1994 and December 1998, 49 were eligible. The progression-free survival (PFS) was 7 months and the overall survival was 12 months. In multivariate analysis, performance status was the only significant defining factor for PFS (P = 0·009). The predominant toxicity was neutropenia and nausea/vomiting. The relative dose intensity of 5-fluorouracil and cisplatin was 89 and 63 per cent respectively. Conclusion: Performance status emerged as a major determining factor for prognosis and patient selection for early postoperative intraperitoneal chemotherapy in patients with advanced gastric cancer after maximally cytoreductive surgery.-
dc.description.statementOfResponsibilityopen-
dc.format.extent460~466-
dc.relation.isPartOfBritish Journal of Surgery-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleTreatment of advanced gastric cancer by palliative gastrectomy, cytoreductive therapy and postoperative intraperitoneal chemotherapy.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Surgery (외과학)-
dc.contributor.googleauthorH. C. Jeung-
dc.contributor.googleauthorS. Y. Rha-
dc.contributor.googleauthorW. I. Jang-
dc.contributor.googleauthorS. H. Noh-
dc.contributor.googleauthorH. C. Chung-
dc.identifier.doi10.1046/j.0007-1323.2001.02048.x-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01281-
dc.contributor.localIdA03773-
dc.contributor.localIdA01316-
dc.contributor.localIdA03794-
dc.relation.journalcodeJ00418-
dc.identifier.urlhttp://onlinelibrary.wiley.com/doi/10.1046/j.0007-1323.2001.02048.x/abstract-
dc.contributor.alternativeNameNoh, Sung Hoon-
dc.contributor.alternativeNameRha, Sun Young-
dc.contributor.alternativeNameChung, Hyun Cheol-
dc.contributor.alternativeNameJeung, Hei Cheul-
dc.contributor.affiliatedAuthorNoh, Sung Hoon-
dc.contributor.affiliatedAuthorChung, Hyun Cheol-
dc.contributor.affiliatedAuthorRha, Sun Young-
dc.contributor.affiliatedAuthorJeung, Hei Cheul-
dc.rights.accessRightsnot free-
dc.citation.volume89-
dc.citation.number4-
dc.citation.startPage460-
dc.citation.endPage466-
dc.identifier.bibliographicCitationBritish Journal of Surgery, Vol.89(4) : 460-466, 2002-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
5. Research Institutes (연구소) > Cancer Metastasis Research Center (암전이연구센터) > 1. Journal Papers

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