Cited 81 times in
rpoB genotypes of Mycobacterium tuberculosis Beijing family isolates from East Asian countries
DC Field | Value | Language |
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dc.contributor.author | 조상래 | - |
dc.date.accessioned | 2016-05-16T11:17:36Z | - |
dc.date.available | 2016-05-16T11:17:36Z | - |
dc.date.issued | 2002 | - |
dc.identifier.issn | 0095-1137 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/144226 | - |
dc.description.abstract | The 81-bp region of the rpoB gene in 66 Rifr Mycobacterium tuberculosis isolates from China, Japan, Korea, and Taiwan was analyzed. Twelve single-nucleotide substitutions in the rpoB gene were detected. The most prevalent mutations were at Ser-531 (52%), Asp-516 (17%), and His-526 (11%). Mutations were not found in seven (11%) of the isolates. Higher mutation rates in 50 Beijing family isolates were found than in other isolates for mutations at Asp-516 (18 and 12.5%, respectively) and His-526 (12 and 6.3%, respectively). The different rates of mutation may reflect the choice of rifamycin analogs. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1091~1094 | - |
dc.relation.isPartOf | JOURNAL OF CLINICAL MICROBIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | DNA-Directed RNA Polymerases/genetics* | - |
dc.subject.MESH | Drug Resistance, Bacterial | - |
dc.subject.MESH | Genotype | - |
dc.subject.MESH | Mutation | - |
dc.subject.MESH | Mycobacteriumtuberculosis/drug effects | - |
dc.subject.MESH | Mycobacteriumtuberculosis/genetics* | - |
dc.subject.MESH | Rifampin/pharmacology | - |
dc.title | rpoB genotypes of Mycobacterium tuberculosis Beijing family isolates from East Asian countries | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Microbiology (미생물학) | - |
dc.contributor.googleauthor | Lishi Qian | - |
dc.contributor.googleauthor | Chiyoji Abe | - |
dc.contributor.googleauthor | Tao Ping Lin | - |
dc.contributor.googleauthor | Ming Chih Yu | - |
dc.contributor.googleauthor | Sang Nae Cho | - |
dc.contributor.googleauthor | Sumin Wang | - |
dc.contributor.googleauthor | James T. Douglas | - |
dc.identifier.doi | 10.1128/JCM.40.3.1091-1094.2002 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03824 | - |
dc.relation.journalcode | J01325 | - |
dc.identifier.eissn | 1098-660X | - |
dc.identifier.pmid | 11880449 | - |
dc.contributor.alternativeName | Cho, Sang Nae | - |
dc.contributor.affiliatedAuthor | Cho, Sang Nae | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 40 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 1091 | - |
dc.citation.endPage | 1094 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CLINICAL MICROBIOLOGY, Vol.40(3) : 1091-1094, 2002 | - |
dc.identifier.rimsid | 56698 | - |
dc.type.rims | ART | - |
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