Cited 11 times in
The Effect of Photodynamic Therapy with Rose Bengal on Posterior Capsule Opacification in Rabbit Eyes
DC Field | Value | Language |
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dc.contributor.author | 고형준 | - |
dc.date.accessioned | 2016-05-16T11:14:48Z | - |
dc.date.available | 2016-05-16T11:14:48Z | - |
dc.date.issued | 2002 | - |
dc.identifier.issn | 0030-3747 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/144119 | - |
dc.description.abstract | We investigated the in vivo effect of photodynamic therapy (PDT) using rose bengal on the development of posterior capsule opacification (PCO). Endocapsular phacoemulsification was performed on white rabbits, which were divided into 4 groups: control group; group 1, treated with visible light only; group 2, treated with rose bengal only, and group 3, treated with PDT. In the case of the PDT group, rose bengal dissolved in sodium hyaluronate was injected into the empty capsular bag and treated with visible light. Three months after surgery, the rabbits were sacrificed and the eyeballs enucleated. The obstruction rate of visible light caused by PCO was measured with an optical powermeter. The mean obstruction rate was 30.6% in the control group, 28.3% in group 1, 19.3% in group 2, and 14.3% in group 3. Group 3 showed a statistically significant decrease in PCO compared with the control group and group 1 (p = 0.0014). Our results suggest that PDT using rose bengal effectively decreased PCO in rabbit eyes. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 107~112 | - |
dc.relation.isPartOf | OPHTHALMIC RESEARCH | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Cataract/drugtherapy* | - |
dc.subject.MESH | Cataract/pathology | - |
dc.subject.MESH | Corneal Edema/chemically induced | - |
dc.subject.MESH | Dose-Response Relationship, Drug | - |
dc.subject.MESH | Osmolar Concentration | - |
dc.subject.MESH | Phacoemulsification* | - |
dc.subject.MESH | Photochemotherapy* | - |
dc.subject.MESH | Rabbits | - |
dc.subject.MESH | RoseBengal/administration & dosage | - |
dc.subject.MESH | RoseBengal/adverseeffects | - |
dc.subject.MESH | RoseBengal/therapeutic use* | - |
dc.title | The Effect of Photodynamic Therapy with Rose Bengal on Posterior Capsule Opacification in Rabbit Eyes | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Ophthalmology (안과학) | - |
dc.contributor.googleauthor | Hyoung J. Koh | - |
dc.contributor.googleauthor | Shin J. Kang | - |
dc.contributor.googleauthor | Seung J. Lim | - |
dc.contributor.googleauthor | Young K. Chu | - |
dc.contributor.googleauthor | Sung C. Lee | - |
dc.contributor.googleauthor | Oh W. Kwon | - |
dc.contributor.googleauthor | Hong B. Kim | - |
dc.identifier.doi | 10.1159/000063652 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00152 | - |
dc.relation.journalcode | J02428 | - |
dc.identifier.eissn | 1423-0259 | - |
dc.identifier.pmid | 12097791 | - |
dc.identifier.url | http://www.karger.com/Article/FullText/63652 | - |
dc.subject.keyword | In vivo | - |
dc.subject.keyword | Photodynamic therapy | - |
dc.subject.keyword | Posterior capsule opacification | - |
dc.subject.keyword | Rose bengal | - |
dc.contributor.alternativeName | Koh, Hyoung Jun | - |
dc.contributor.affiliatedAuthor | Koh, Hyoung Jun | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 34 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 107 | - |
dc.citation.endPage | 112 | - |
dc.identifier.bibliographicCitation | OPHTHALMIC RESEARCH, Vol.34(3) : 107-112, 2002 | - |
dc.identifier.rimsid | 55599 | - |
dc.type.rims | ART | - |
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