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False negative interpretation of FDG positron emission tomography in a patient with Hodgkin's lymphoma

Authors
 Woojin Kim  ;  Mijin Yun  ;  Naheel Alnafisi  ;  Marc Hickeson  ;  Abass Alavi 
Citation
 CLINICAL NUCLEAR MEDICINE, Vol.27(5) : 367-368, 2002 
Journal Title
 CLINICAL NUCLEAR MEDICINE 
ISSN
 0363-9762 
Issue Date
2002
MeSH
Adult ; Axilla ; Catheterization, Central Venous ; Dose-Response Relationship, Drug ; False Negative Reactions ; Female ; Fluorodeoxyglucose F18/administration & dosage* ; Fluorodeoxyglucose F18/pharmacokinetics ; Hodgkin Disease/diagnostic imaging* ; Hodgkin Disease/metabolism ; Humans ; Infusions, Intravenous ; Lymph Nodes/diagnostic imaging ; Lymph Nodes/metabolism ; Time Factors ; Tomography, Emission-Computed
Keywords
Dose Infiltration ; F-18 Fluorodeoxyglucose ; Image Quality ; Lesion Detectability ; Positron Emission Tomography
Abstract
Differences in image quality of F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) can affect lesion detectability on acquired images. The authors describe a 26-year-old woman with a history of Hodgkin’s disease whose residual tumor was not detected initially after dose infiltration and imaging acquisition 60 minutes after injection at a glucose level of 106 mg/dl. The residual tumor was detected 2 weeks later after F-18 FDG injection via a central venous access line, to avoid dose infiltration, and imaging performed 90 minutes after injection at a glucose level of 82 mg/dl. This case demonstrates various parameters, such as injection dose, postinjection scan delay, and blood glucose level, that can affect FDG-PET image quality and lesion detectability as a result.
Full Text
http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00003072-200205000-00015&LSLINK=80&D=ovft
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학교실) > 1. Journal Papers
Yonsei Authors
Yun, Mi Jin(윤미진) ORCID logo https://orcid.org/0000-0002-1712-163X
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/144073
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