Cited 7 times in
Induction of telomerase activity during an early burst of proliferation in pancreatic regeneration
DC Field | Value | Language |
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dc.contributor.author | 박영년 | - |
dc.contributor.author | 박찬일 | - |
dc.contributor.author | 오봉경 | - |
dc.date.accessioned | 2016-05-16T11:09:39Z | - |
dc.date.available | 2016-05-16T11:09:39Z | - |
dc.date.issued | 2002 | - |
dc.identifier.issn | 0304-3835 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/143924 | - |
dc.description.abstract | Telomerase activity (TA) and telomerase reverse transcriptase (rTERT) were investigated in Sprague–Dawley rats, killed at 6 and 12 h, and 1, 2, 3, 7, and 14 days after 90% pancreatectomy (px), by TRAPeze enzyme-linked immunosorbent assay telomerase detection and reverse transcriptase–polymerase chain reaction. TA increased at 2 days and reached a maximum at 3 days after px, when the small ductules showed the highest proliferation activity. After 3 days, TA decreased to basal levels as the ductules differentiated into new endocrine and exocrine pancreas. The expression of rTERT showed a correlation with TA. These results suggest telomerase is actively regulated during pancreatic regeneration. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 93~98 | - |
dc.relation.isPartOf | CANCER LETTERS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Amylases/blood | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Blood Glucose/analysis | - |
dc.subject.MESH | DNA-Binding Proteins | - |
dc.subject.MESH | Enzyme Induction | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Pancreas/cytology | - |
dc.subject.MESH | Pancreas/enzymology* | - |
dc.subject.MESH | Pancreas/physiology* | - |
dc.subject.MESH | Proliferating Cell Nuclear Antigen/analysis | - |
dc.subject.MESH | RNA, Messenger/analysis | - |
dc.subject.MESH | Rats | - |
dc.subject.MESH | Rats, Sprague-Dawley | - |
dc.subject.MESH | Regeneration/physiology* | - |
dc.subject.MESH | Reverse Transcriptase Polymerase Chain Reaction | - |
dc.subject.MESH | Telomerase/biosynthesis* | - |
dc.subject.MESH | Telomerase/genetics | - |
dc.title | Induction of telomerase activity during an early burst of proliferation in pancreatic regeneration | - |
dc.type | Article | - |
dc.contributor.college | Researcher Institutes (부설 연구소) | - |
dc.contributor.department | Cancer Metastasis Research Center (암전이연구센터) | - |
dc.contributor.googleauthor | Bong Kyeong Oha | - |
dc.contributor.googleauthor | Je Kyung Seong | - |
dc.contributor.googleauthor | Jeung Eun Lee | - |
dc.contributor.googleauthor | Kwang Jo Chae | - |
dc.contributor.googleauthor | Kyung Jin Roh | - |
dc.contributor.googleauthor | Chanil Park | - |
dc.contributor.googleauthor | Young Nyun Park | - |
dc.identifier.doi | 10.1016/S0304-3835(02)00320-8 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01563 | - |
dc.contributor.localId | A01710 | - |
dc.contributor.localId | A02369 | - |
dc.relation.journalcode | J00448 | - |
dc.identifier.eissn | 1872-7980 | - |
dc.identifier.pmid | 12183080 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0304383502003208 | - |
dc.subject.keyword | Pancreas | - |
dc.subject.keyword | Regeneration | - |
dc.subject.keyword | Telomerase | - |
dc.subject.keyword | Telomerase reverse transcriptase | - |
dc.subject.keyword | Proliferation | - |
dc.subject.keyword | Pancreatectomy | - |
dc.contributor.alternativeName | Park, Young Nyun | - |
dc.contributor.alternativeName | Park, Chan Il | - |
dc.contributor.alternativeName | Oh, Bong Kyeong | - |
dc.contributor.affiliatedAuthor | Park, Young Nyun | - |
dc.contributor.affiliatedAuthor | Park, Chan Il | - |
dc.contributor.affiliatedAuthor | Oh, Bong Kyeong | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 186 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 93 | - |
dc.citation.endPage | 98 | - |
dc.identifier.bibliographicCitation | CANCER LETTERS, Vol.186(1) : 93-98, 2002 | - |
dc.identifier.rimsid | 39514 | - |
dc.type.rims | ART | - |
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