340 557

Cited 0 times in

생후 6주(4.7 kg) 때 치료적 백혈구성분채집술을 시행한 영아 백혈병 1례

Other Titles
 Therapeutic Leukapheresis for Acute Lymphoblastic Leukemia with Severe Hyperleukocytosis in a Six-Week-Old Infant (4.7 kg) 
 변지윤  ;  신경미  ;  원성철  ;  유철주  ;  임현숙  ;  김현옥 
 Korean Journal of Pediatric Hematology-Oncology (대한소아혈액종양학회지), Vol.9(2) : 250-254, 2002 
Journal Title
Korean Journal of Pediatric Hematology-Oncology(대한소아혈액종양학회지)
Issue Date
Therapeutic leukapheresis ; Acute lymphoblastic leukemia ; Hyperleukocytosis ; Ifant
We report a 4.7 kg infant who received a therapeutic leukapheresis as an immediate treatment for acute lymphoblastic leukemia with severe hyperleukocytosis. By decreasing the number of circulating white blood cells, therapeutic leukapheresis helps prevent the risks of hyperviscosity and cerebrovascular and pulmonary leukostasis. In addition, it potentially reduces metabolic and renal complications associated with rapid cell lysis when applied before chemotherapy. This six-week-old female presented with vomiting for 15 days. Initial WBC count was 1,532,800/μL. After placement of 4 french two-lumen central venous catheter in both femoral vein, the CS 3000 plus was primed with 250 mL of paternal whole blood mixed with 150 mL of normal saline. After therapeutic leukapheresis, the CBC showed WBC count of 560,000/μL. Our successful experience in performing this procedure suggests that therapeutic leukapheresis be a feasible treatment even for very young infants with hyperleukocytosis.
Files in This Item:
T200205488.pdf Download
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers
Yonsei Authors
Lyu, Chuhl Joo(유철주) ORCID logo https://orcid.org/0000-0001-7124-7818
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.