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칼시토닌 발현과 아밀로이드 축적을 보인 중이의 유암종 -1예 보고-

Other Titles
 Calcitonin Producing Middle Ear Carcinoid with Amyloid Deposition -A Case Report- 
Authors
 임범진  ;  양우익  ;  홍순원  ;  박찬일 
Citation
 KOREAN JOURNAL OF PATHOLOGY , Vol.36(2) : 115-118, 2002 
Journal Title
 KOREAN JOURNAL OF PATHOLOGY 
ISSN
 0379-1149 
Issue Date
2002
Keywords
Carcinoid Tumor-Ear ; Middle-Calcitonin-Amyloid
Abstract
Carcinoid tumor of the middle ear cavity is a rare neoplasm of low malignant potential. It grows slowly and rarely metastasizes. We recently experienced a case of carcinoid tumor of the middle ear cavity occurring in a 51-year-old female who was presented with hearing loss and tinnitus of the right ear. A 1 cm sized pinkish soft mass was noted in the promontory of the middle ear. Histologically, the mass was composed of nests and cords of tumor cells with slightly pleomorphic nuclei and eosinophilic cytoplasm. The extracellular matrix was glassy pink, homogeneous and exhibited apple green birefringence under a polarized light microscope after Congo red staining. The tumor cells showed immunoreactivity for cytokeratin, chromogranin A, synaptophysin, neuron-specific enolase and calcitonin. Electron microscopic examination confirmed the presence of neurosecretory granules. The production of calcitonin and amyloid by the tumor cells suggests the possible relationship of this tumor to the thyroid C cells.
Files in This Item:
T200204441.pdf Download
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
Yonsei Authors
Park, Chan Il(박찬일)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/143713
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