352 1018

Cited 0 times in

항균제가 없는 환경에서 항균제 감수성 그람음성 간균 공존의 내성 그람음성 간균에 대한 영향

DC Field Value Language
dc.contributor.author염종화-
dc.contributor.author용동은-
dc.contributor.author이경원-
dc.date.accessioned2016-05-16T11:03:48Z-
dc.date.available2016-05-16T11:03:48Z-
dc.date.issued2002-
dc.identifier.issn1598-8112-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/143704-
dc.description.abstractBackground: Carrying antimicrobial resistance genes is a burden to bacteria. Therefore, in the absence of antimicrobial selective pressure, susceptible bacteria are expected to replace resistant ones. The cost was reported to decrease with time, but the effect of different species of susceptible bacteria on extended-specturm β-lactamase (ESBL)-. AMPC β-lactamase-, and VIM-2 metallo-β-lactamase-producing gram-negative bacilli are not known. The aim of this study was to determine the effect in vitro. Methods: Antimicrobial-susceptible and -resistant strains of Escherichia coli, enterobacter aerogenes, Klebsiella pneumoniae, and Acinetobacter baumannii were subcultured daily in glucose limited minimal salt medium at 30℃ and 37℃, and the numbers of cells (CFU/㎖) were determined by culturing on Mueller-Hinton agar and MacConkey agar plates. Results: Continued incubation without subculture of both individual and mixed cultures at 37℃ showed higher counts of a ESBL-producing K. pneumoniae than a susceptible E. coli. Daily subcultures of two strains in a tube showed the counts were:ESBL-producing K. pneumoniae >susceptible E. coli; susceptible E. aerogenes >ESBL-producing K. pneumoniae; susceptible E. aerogenes >VIM-2-β-lactamase-producing Acinetobacter baumannii. The counts were similar for susceptible K. pneumoniae and AmpC β-lactamase-hyperproducing E. aerogenes. Initial low count of a susceptible E. coli and an ESBL-producing K. pneumoniae at 30℃ gradually increased with continued subculture. Conclusion: Growth of not all resistant bacteria are slower and the growth improves withcontinued subculture. Coexistence of a susceptible bacteria with resistant bacteria in GLMS medium both at 30℃ and 37℃ does not reduce the number of resistant bacteria.-
dc.description.statementOfResponsibilityopen-
dc.format.extent9~17-
dc.relation.isPartOfINFECTION AND CHEMOTHERAPY (감염과 화학요법)-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.title항균제가 없는 환경에서 항균제 감수성 그람음성 간균 공존의 내성 그람음성 간균에 대한 영향-
dc.title.alternativeEffect of Coexistence of Antimicrobial-susceptible Gram-negative Bacilli on the Resistant Gram-negative Bacilli in the Absence of Antimicrobial Agents-
dc.typeArticle-
dc.contributor.collegeResearcher Institutes (부설 연구소)-
dc.contributor.department세균내성연구소-
dc.contributor.googleauthor용동은-
dc.contributor.googleauthor최응칠-
dc.contributor.googleauthor이경원-
dc.contributor.googleauthor염종화-
dc.contributor.googleauthor정윤섭-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02352-
dc.contributor.localIdA02423-
dc.contributor.localIdA02649-
dc.relation.journalcodeJ01054-
dc.subject.keywordAntimicrobial resistance-
dc.subject.keywordCost of resistance-
dc.subject.keywordFitness-
dc.contributor.alternativeNameYum, Jong Hwa-
dc.contributor.alternativeNameYong, Dong Eun-
dc.contributor.alternativeNameLee, Kyung Won-
dc.contributor.affiliatedAuthorYum, Jong Hwa-
dc.contributor.affiliatedAuthorYong, Dong Eun-
dc.contributor.affiliatedAuthorLee, Kyung Won-
dc.rights.accessRightsfree-
dc.citation.volume34-
dc.citation.number1-
dc.citation.startPage9-
dc.citation.endPage17-
dc.identifier.bibliographicCitationINFECTION AND CHEMOTHERAPY (감염과 화학요법), Vol.34(1) : 9-17, 2002-
dc.identifier.rimsid38611-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Research Institute (부설연구소) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.